Recombinant Human FGF-16

Name

Recombinant Human FGF-16 (Recombinant Human Fibroblast Growth Factor-16; rHuFGF-16)；重组人成纤维细胞生长因子16

Synonyms

MF4; FGF-16

Purity

>98% by SDS-PAGE and HPLC analyses.

Biological Activity

Fully biologically active when compared to standard. The ED50 as determined by thymidine uptake assay using FGF-receptors transfected BaF3 cells is less than 0.5ng/ml, corresponding to a specific activity of >2.0×10⁶IU/mg.

Physical Appearance

Sterile Colorless liquid.

Formulation

Supplied as a 0.2μm filtered solution in 20mM Tris-HCl, 1M NaCl, pH 9.0, with 0.02% Tween-20, 10% Glycerol.

Endotoxin

Less than 0.1EU/μg of rHuFGF-16 as determined by LAL method.

Reconstitution

N/A

Category

Cytokine

Background

Fibroblast growth factor 16 (FGF-16) belongs to the large FGF family. All FGF family members are heparin-binding growth factors with a core 120 amino acid (a.a.) FGF domain that allows for a common tertiary structure. FGF-16 was originally identified in rat heart tissue by homology based polymerase chain reaction. Human FGF-16 cDNA predicts a 207 aa precursor protein with one N-linked glycosylation site. FGF-16 lacks a typical signal peptide, but is efficiently generated by mechanisms other than the classical protein secretion pathway. Among FGF family members, FGF-16 is most similar to FGF-9, sharing 73% aa sequence homology. Human FGF-16 shares 99% and 98.6% aa sequence identity with the mouse and rat FGF-16, respectively.

Amino Acid Sequence

AEVGGVFASL DWDLHGFSSS LGNVPLADSP GFLNERLGQI EGKLQRGSPT DFAHLKGILR RRQLYCRTGF HLEIFPNGTV HGTRHDHSRF GILEFISLAV GLISIRGVDS GLYLGMNERG ELYGSKKLTR ECVFREQFEE NWYNTYASTL YKHSDSERQY YVALNKDGSP REGYRTKRHQ KFTHFLPRPV DPSKLPSMSR DLFHYR

产品编号

产品名称

包装

KL-5482-5μg

Recombinant Human FGF-16

5μg

KL-5482-25μg

Recombinant Human FGF-16

25μg

KL-5482-100μg

Recombinant Human FGF-16

100μg

KL-5482-1mg

Recombinant Human FGF-16

1mg

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说明书

1份