DACH1 Antibody

￥2800 100ul 起订

其他更新日期：2020-01-15

佰思诺（天津）生物科技有限公司

非会员

联系人：佰思诺

手机：18322122675 拨打

邮箱：1073531646@qq.com

产品详情:

英文名称：: DACH1 Antibody

克隆性：: 单克隆

适应物种：: human, mouse, rat

货号：: EL800776-100

免疫原：: DACH1 fusion protein ag1354

规格：: 100ul

应用范围：: ELISA, CHIP, IF, IHC, IP, WB

浓度：: 1mg/ml

形态：: Liquid

抗体名：: DACH1 Antibody

宿主：: Rabbit

标记物：: Unconjugated

抗体英文名：: DACH1 Antibody

亚型：: IgG

靶点：: DACH1

保存条件：: PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC.Aliquoting is unnecessary for -20oC storage.

DACH1, a homologue of the Drosophila dachshund gene, is a key regulator of cell fate determination during eye, leg, and brain development in the fly. Through interacting with NCoR and Smad4, DACH1 is able to inhibit the transforming growth factor-beta (TGF-beta) signaling pathway. DACH1 can inhibit breast cancer cellular proliferation via cyclin D1, suggesting a possible role in tumor suppression. Additionally, DACH1 plays an important role in negative regulation of RANKL (Receptor activator of NF-kappaB ligand ) gene expression in marrow stromal/preosteoblast cells, and loss of DACH1 expression might be involved in endometrial cancer progression. Four isoforms of DACH1 are produced by alternative splicing. This antibody is a rabbit polyclonal antibody raised against residues near the C terminus of human DACH1.详情请登录EterLife官网：http://www.eterlife.com/

DACH1 Antibody;抗体