Anti-CPE antibody

Anti-CPE antibody

Cat. No.    JC224408
Package    25 μl/100 μl/200 μl
Storage    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Product overview
Description                   Anti-CPE rabbit polyclonal antibody
Applications        ELISA, WB, IHC 
Immunogen               Fusion protein of human CPE
Reactivity                 Human, Mouse, Rat
Content                     0.5 mg/ml
Host species               Rabbit
Ig class                  Immunogen-specific rabbit IgG
Purification                 Antigen affinity purification

Target information
Symbol                 CPE
Full name                 carboxypeptidase E
Synonyms    CPH
Swissprot    P16870

Target Background
This gene encodes a member of the M14 family of metallocarboxypeptidases. The encoded preproprotein is proteolytically processed to generate the mature peptidase. This peripheral membrane protein cleaves C-terminal amino acid residues and is involved in the biosynthesis of peptide hormones and neurotransmitters, including insulin. This protein may also function independently of its peptidase activity, as a neurotrophic factor that promotes neuronal survival, and as a sorting receptor that binds to regulated secretory pathway proteins, including prohormones. Mutations in this gene are implicated in type 2 diabetes.

Anti-CPE antibody
Applications
Immunohistochemistry
Predicted cell location: Nucleus
Positive control: Human colorectal cancer
Recommended dilution: 25-100    Predicted cell location: Nucleus
Positive control: Human tonsil
Recommended dilution: 25-100