human IL2 重组蛋白; T-cell growth factor;TCGF

产品描述：

产品名称：Recombinant human IL2 protein

产品别名：T-cell growth factor； TCGF

形态：Protein is supplied in 20 mM Tris, 300 mM NaCl, 10% Glycerol, pH 7.5.

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保存方法：Clear solution, frozen.Store at -70°C for one year. At first use, aliquot and store at -70°C to avoid multiple freeze-thaws.

产品描述：

Recombinant human IL2 protein aa1-153 was produced in mammalian cells with His-DYK tag. The theoretical molecular weight of recombinant IL2 is 15 kDa. Purified IL2 protein is near the position of 17 kDa on SDS-PAGE gel under reduced condition.
IL2 protein is purified by proprietary chromatographic techniques. 

Entrez Gene summary for IL2:

Summary: The protein encoded by this gene is a secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7). The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis-like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli.

UniProtKB/Swiss-Prot: P60568 (IL2_HUMAN)

Function: Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells.

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