Bcl-XL

产品英文名称：
Recombinant Human B-Cell Leukemia/Lymphoma 2 XL

英文简称:
Bcl-XL

中文名称:
重组人B细胞淋巴瘤因子2 XL

背景资料:
Bcl-XL is a transmembrane protein located in the mitochondrial membranes of cells that are long-lived and postmitotic， such as adult brain cells. It plays arole in the signal transduction pathway of the FAS-Ligand. Bcl-XL is an anti-apoptotic protein which is a member of the Bcl-2 family which are able to form heterodimers， and this is an significant event in the regulation of apoptosis. BCL-XL is involved in the survival of cancer cells.Bcl-xL is the leading monitor of apoptosis/active cell suicide. Bcl-xL has cell death repressor activity and therefore acts as a survival protein.

产品描述:
Bcl-XL Human Recombinant produced in E.Coli is a single， non-glycosylated polypeptide chain containing amino acids 1-210.The Bcl-XL is purified by proprietary chromatographic techniques.
来源宿主:
大肠杆菌中重组表达

序列:


溶解建议:
Sterile Filtered White lyophilized （freeze-dried） powder. The protein contains 10mM Tris-HCL pH-8， 1mM EDTA and 250mM NaCl. Suspend BclXL in 100?l of 0.5M Acetic acid， over night at 4°C.Dilute 10 fold into selected buffer system.Bcl-XL has tendency to form intramolecular disulfide bond， 5mM DTT is recommended in assay buffer. When running SDS-PAGE gel， 10mM DTT is recommended.

保存建议：
Lyophilized Bcl-XL although stable at room temperature for 3 weeks， should be stored desiccated below -18℃. Upon reconstitution Bcl-XL should be stored at 4℃ between 2-7 days and for future use below-18℃.For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.Please prevent freeze-thaw cycles.
其他简介：

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