CENPB

产品英文名称：
Recombinant Human Centromere Protein-B

英文简称:
CENPB

中文名称:
重组人着丝粒蛋白-B

背景资料:
Centromere proteins are a group of proteins which form and/or mediate the function of centromeres， the central structures of chromosomes to which spindle fibers/microtubuli attach and pull the chromosomes apart in cell division. Currently， 9 centromere proteins are known and designated CENPA to CENP-I. Most of the centromere proteins are targets of autoantibodies， the anti-centromere antibodies.CENPB is the most important of the centromeric autoantigens: it has a molecular weight of approx. 66 kDa and plays an important role in the formation of the centromeric chromatin. CENPB antibodies are present in the sera of up to 80% of patients with CREST syndrome.

产品描述:
CENPB Human Recombinant produced in SF9 is a glycosylated， polypeptide chain having a molecular mass of 65，940 Dalton.CENPB is expressed with a -6x His tag and purified by proprietary chromatographic techniques.
来源宿主:
昆虫Sf9细胞中重组表达

序列:


溶解建议:
Sterile Filtered liquid formulation. CENPB is supplied in 20mM HEPES buffer pH-7.6， 250mM sodium chloride， and 20% glycerol.

保存建议：
Store at 4℃ if entire vial will be used within 2-4 weeks.Store， frozen at -20℃ for longer periods of time.Avoid multiple freeze-thaw cycles.
其他简介：

  ProSpec是一家全球著名细胞因子蛋白及相关抗体生产和研发品牌。ProSpec的生产和研发工厂位于以色列，专注于蛋白（重组及合成）生产研发，其独有的细菌和哺乳动物表达和蛋白折叠技术使其能在17年内成长为国际一流的科研级蛋白供应商。目前ProSpec可以提供细胞因子，生长因子，激素，信号蛋白，病毒抗原等近800种重组蛋白和100多种抗体，是世界上提供蛋白品种最多的公司之一，领先的生产工艺和规模使其可以提供毫克到克级蛋白，价格优于同类公司。绝大部分产品是天然成熟型蛋白，而不含有标签蛋白。考虑到大部分研究者希望能更灵活地配制蛋白溶液，ProSpec-Tany绝大部分产品没有添加保护剂或盐，这就对工艺提出了更高的要求。同时，ProSpec-Tany绝大部分产品为冻干粉，因此易于运输和保存。
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