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网站主页 RECOMBINANT HUMAN MACROPHAGE COLONY-STIMULATING FACTOR 1 RECEPTOR/M-CSF R/CSF1R/CD115 Recombinant Human Macrophage Colony-stimulating Factor 1 Receptor/M-CSF R/CSF1R/CD115
  • Recombinant Human  Macrophage Colony-stimulating Factor 1 Receptor/M-CSF R/CSF1R/CD115

Recombinant Human Macrophage Colony-stimulating Factor 1 Receptor/M-CSF R/CSF1R/CD115

Recombinant Human Macrophage Colony-stimulating Factor 1 Receptor/M-CSF R/CSF1R/CD115
6720.00 500ug 起订
10640.00 1mg 起订
1170.00 50ug 起订
560.00 10ug 起订
北京 更新日期:2024-12-23

北京索莱宝科技有限公司

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产品详情:

中文名称:
Recombinant Human Macrophage Colony-stimulating Factor 1 Receptor/M-CSF R/CSF1R/CD115
英文名称:
Recombinant Human Macrophage Colony-stimulating Factor 1 Receptor/M-CSF R/CSF1R/CD115
Derived from:
Human cells
Endotoxin:
Less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.
Formulation:
Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
Purity:
Greater than 95% as determined by reducing SDS-PAGE.
产品编号:
P00225

Recombinant Human Macrophage Colony-stimulating Factor 1 Receptor is produced by our Mammalian expression system and the target gene encoding Ile20-Pro517 is expressed with a 6His tag at the C-terminus.

Background

Macrophage colony-stimulating factor 1 receptor (CSF1R) is a member of the type III subfamily of receptor tyrosine kinases that also includes receptors for SCF and PDGF. These receptors each contain five immunoglobulin-like domains in their extracellular domain (ECD) and a split kinase domain in their intracellular region. CSF1R is expressed primarily on cells of the monocyte/macrophage lineage, dendritic cells, stem cells and in the developing placenta. CSF1 and its receptor (CSF1R, product of c-fms proto-oncogene) were initially implicated as essential for normal monocyte development as well as for trophoblastic implantation. It plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone and tooth development. It is required for normal male and female fertility, and for normal development of milk ducts and acinar structures in the mammary gland during pregnancy. Aberrant expression of CSF1 or CSF1R may play a role in inflammatory diseases, such as rheumatoid arthritis, glomerulonephritis, atherosclerosis, and allograft rejection.

Known as

Macrophage colony-stimulating factor 1 receptor; CSF-1 receptor; CSF-1-R; CSF-1R; M-CSF-R; Proto-oncogene c-Fms; CD115; CSF1R; FMS

Reconstitution

Always centrifuge tubes before opening. Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in ddH2O.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Storage

Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at < -20°C for 3 months
Recombinant Human Macrophage Colony-stimulating Factor 1 Receptor/M-CSF R/CSF1R/CD115;细胞生物学

公司简介

北京索莱宝科技有限公司是一家集研发、生产、销售、服务于一体的高科技生物企业。技术推广;技术转让;技术咨询;技术服务;生物试剂技术开发;销售生物试剂盒、实验室专用化学试剂、实验室专用设备、办公用品、化工产品(不含危险化学品)、计算机软件及辅助设备;货物进出口、技术进出口、代理进出口;委托加工生产生物制品、生化制品、化工产品(不含危险化学品);生产生物试剂盒;批发第一类医疗器械、第二类医疗器械;批发第三类医疗器械。

成立日期 (21年)
注册资本 1000万元
员工人数 50-100人
年营业额 ¥ 500万-1000万
经营模式 贸易,工厂,试剂
主营行业 分析化学,生物化工,化学试剂,医药原料,仪器耗材

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