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Anti-XBP1 Polyclonal Antibody

Anti-XBP1 Polyclonal Antibody
960.00 50ul 起订
1600.00 100ul 起订
北京 更新日期:2024-11-27

北京索莱宝科技有限公司

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产品详情:

中文名称:
Anti-XBP1 Polyclonal Antibody
英文名称:
Anti-XBP1 Polyclonal Antibody
Gene ID:
7494
Public Immunogen Range:
Recombinant protein of human XBP1
Subcellular Locations:
Cytoplasm Endoplasmic reticulum Nucleus
Swiss Prot:
P17861
保存:
Store at -20°C. Avoid freeze / thaw cycles.
别名:
TREB-5;TREB5;XBP-1;XBP2
产品编号:
K002951P
储存液:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法:
Affinity purification
蛋白分子量:
29/40kDa
克隆类型:
Polyclonal Antibody
免疫原:
Recombinant protein of human XBP1
宿主:
Rabbit
稀释比例:
WB 1:500-2000. IF 1:50-200.
性状:
液体
亚型:
IgG
应用:
WB IF
英文名称:
Anti-XBP1 Polyclonal Antibody

背景资料

This gene encodes a transcription factor that regulates MHC class II genes by binding to a promoter element referred to as an X box. This gene product is a bZIP protein, which was also identified as a cellular transcription factor that binds to an enhancer in the promoter of the T cell leukemia virus type 1 promoter. It may increase expression of viral proteins by acting as the DNA binding partner of a viral transactivator. It has been found that upon accumulation of unfolded proteins in the endoplasmic reticulum (ER), the mRNA of this gene is processed to an active form by an unconventional splicing mechanism that is mediated by the endonuclease inositol-requiring enzyme 1 (IRE1). The resulting loss of 26 nt from the spliced mRNA causes a frame-shift and an isoform XBP1(S), which is the functionally active transcription factor. The isoform encoded by the unspliced mRNA, XBP1(U), is constitutively expressed, and thought to function as a negative feedback regulator of XBP1(S), which shuts off transcription of target genes during the recovery phase of ER stress. A pseudogene of XBP1 has been identified and localized to chromosome 5.
Anti-XBP1 Polyclonal Antibody;抗体

公司简介

北京索莱宝科技有限公司是一家集研发、生产、销售、服务于一体的高科技生物企业。技术推广;技术转让;技术咨询;技术服务;生物试剂技术开发;销售生物试剂盒、实验室专用化学试剂、实验室专用设备、办公用品、化工产品(不含危险化学品)、计算机软件及辅助设备;货物进出口、技术进出口、代理进出口;委托加工生产生物制品、生化制品、化工产品(不含危险化学品);生产生物试剂盒;批发第一类医疗器械、第二类医疗器械;批发第三类医疗器械。

成立日期 (21年)
注册资本 1000万元
员工人数 50-100人
年营业额 ¥ 500万-1000万
经营模式 贸易,工厂,试剂
主营行业 分析化学,生物化工,化学试剂,医药原料,仪器耗材

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