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  • Anti-XAB2 Polyclonal Antibody

Anti-XAB2 Polyclonal Antibody

Anti-XAB2 Polyclonal Antibody
960.00 50ul 起订
1600.00 100ul 起订
北京 更新日期:2024-09-14

北京索莱宝科技有限公司

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联系人:索莱宝
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产品详情:

中文名称:
Anti-XAB2 Polyclonal Antibody
英文名称:
Anti-XAB2 Polyclonal Antibody
Gene ID:
56949
Public Immunogen Range:
A synthetic peptide of human XAB2
Subcellular Locations:
Nucleus
Swiss Prot:
Q9HCS7
保存:
Store at -20°C. Avoid freeze / thaw cycles.
别名:
HCNP;HCRN;SYF1;NTC90
产品编号:
K007972P
储存液:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法:
Affinity purification
蛋白分子量:
100kDa
交叉反应:
Human Mouse Rat
克隆类型:
Polyclonal Antibody
免疫原:
A synthetic peptide of human XAB2
宿主:
Rabbit
稀释比例:
WB 1:500-2000. IHC 1:25-100.
性状:
液体
亚型:
IgG
应用:
WB IHC
英文名称:
Anti-XAB2 Polyclonal Antibody

背景资料

HCNP, also known as XAB2 (Xeroderma pigmentosum group A (XPA) binding protein 2), HCRN, SYF1 or NTC90, is a nuclear protein that participates in transcription, transcription-coupled repair (TCR) and pre-mRNA splicing. It contains fifteen tetratricopeptide repeat motifs and associates with nucleotide excision repair machinery. More specifically, HCNP associates with Cockayne syndrome group A and B proteins (CSA and CSB), RNA Polymerase II (Pol II) and XPA in response to DNA damage and is believed to function in the TCR pathway. HCNP also functions as an essential component of a pre-mRNA splicing complex of the spliceosome (composed of AQR (aquarius), PRP19, CCDC16, HCNP, ISY1 and Cyclophilin E) and is required for proper RNA synthesis in the cell. In addition, HCNP functions as a component of the RAR corepressor complex with RAR? and HDAC3 and exhibits an inhibitory effect on ATRA-induced cell differentiation. This suggests that HCNP may function as useful target in cancer therapy.
Anti-XAB2 Polyclonal Antibody;抗体

公司简介

北京索莱宝科技有限公司是一家集研发、生产、销售、服务于一体的高科技生物企业。技术推广;技术转让;技术咨询;技术服务;生物试剂技术开发;销售生物试剂盒、实验室专用化学试剂、实验室专用设备、办公用品、化工产品(不含危险化学品)、计算机软件及辅助设备;货物进出口、技术进出口、代理进出口;委托加工生产生物制品、生化制品、化工产品(不含危险化学品);生产生物试剂盒;批发第一类医疗器械、第二类医疗器械;批发第三类医疗器械。

成立日期 (21年)
注册资本 1000万元
员工人数 50-100人
年营业额 ¥ 500万-1000万
经营模式 贸易,工厂,试剂
主营行业 分析化学,生物化工,化学试剂,医药原料,仪器耗材

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