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Anti-TRAF2 Polyclonal Antibody

Anti-TRAF2 Polyclonal Antibody
1600.00 100ul 起订
960.00 50ul 起订
北京 更新日期:2024-10-18

北京索莱宝科技有限公司

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联系人:索莱宝
电话:010-50973130拨打
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邮箱:3193328036@qq.com

产品详情:

中文名称:
Anti-TRAF2 Polyclonal Antibody
英文名称:
Anti-TRAF2 Polyclonal Antibody
Gene ID:
7186
Public Immunogen Range:
Recombinant protein of human TRAF2
Subcellular Locations:
Cytoplasm
Swiss Prot:
Q12933
保存:
Store at -20°C. Avoid freeze / thaw cycles.
别名:
MGC:45012;TRAP;TRAP3
产品编号:
K001771P
储存液:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法:
Affinity purification
蛋白分子量:
56kDa
交叉反应:
Human Mouse Rat
克隆类型:
Polyclonal Antibody
克隆类型2:
Polyclonal Antibody
免疫原:
Recombinant protein of human TRAF2
宿主:
Rabbit
稀释比例:
WB 1:500-2000. IHC 1:50-200.IF 1:20-100.
性状:
液体
亚型:
IgG
应用:
WB IHC IF
应用2:
WB IHC IF
英文名称:
Anti-TRAF2 Polyclonal Antibody

背景资料

The protein encoded by this gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from members of the TNF receptor superfamily. This protein directly interacts with TNF receptors, and forms a heterodimeric complex with TRAF1. This protein is required for TNF-alpha-mediated activation of MAPK8/JNK and NF-kappaB. The protein complex formed by this protein and TRAF1 interacts with the inhibitor-of-apoptosis proteins (IAPs), and functions as a mediator of the anti-apoptotic signals from TNF receptors. The interaction of this protein with TRADD, a TNF receptor associated apoptotic signal transducer, ensures the recruitment of IAPs for the direct inhibition of caspase activation. BIRC2/c-IAP1, an apoptosis inhibitor possessing ubiquitin ligase activity, can unbiquitinate and induce the degradation of this protein, and thus potentiate TNF-induced apoptosis. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of only one transcript has been determined.
Anti-TRAF2 Polyclonal Antibody;抗体

公司简介

北京索莱宝科技有限公司是一家集研发、生产、销售、服务于一体的高科技生物企业。技术推广;技术转让;技术咨询;技术服务;生物试剂技术开发;销售生物试剂盒、实验室专用化学试剂、实验室专用设备、办公用品、化工产品(不含危险化学品)、计算机软件及辅助设备;货物进出口、技术进出口、代理进出口;委托加工生产生物制品、生化制品、化工产品(不含危险化学品);生产生物试剂盒;批发第一类医疗器械、第二类医疗器械;批发第三类医疗器械。

成立日期 (21年)
注册资本 1000万元
员工人数 50-100人
年营业额 ¥ 500万-1000万
经营模式 贸易,工厂,试剂
主营行业 分析化学,生物化工,化学试剂,医药原料,仪器耗材

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