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  • Anti-TNFSF11 Polyclonal Antibody

Anti-TNFSF11 Polyclonal Antibody

Anti-TNFSF11 Polyclonal Antibody
1600.00 100ul 起订
960.00 50ul 起订
北京 更新日期:2024-05-17

北京索莱宝科技有限公司

VIP8年
联系人:索莱宝
电话:010-50973130拨打
手机:4009686088 拨打
邮箱:3193328036@qq.com

产品详情:

中文名称:
Anti-TNFSF11 Polyclonal Antibody
英文名称:
Anti-TNFSF11 Polyclonal Antibody
Gene ID:
8600
Public Immunogen Range:
A synthetic peptide of human TNFSF11
Subcellular Locations:
Cytoplasm
Swiss Prot:
O14788
保存:
Store at -20°C. Avoid freeze / thaw cycles.
别名:
ODF;OPGL;sOdf;CD254;OPTB2;RANKL;TNLG6B;TRANCE;hRANKL2
产品编号:
K008348P
储存液:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法:
Affinity purification
蛋白分子量:
36kDa
交叉反应:
Human Mouse Rat
克隆类型:
Polyclonal Antibody
免疫原:
A synthetic peptide of human TNFSF11
宿主:
Rabbit
稀释比例:
WB 1:200-1000. IHC 1:30-150.
性状:
液体
亚型:
IgG
应用:
WB IHC
英文名称:
Anti-TNFSF11 Polyclonal Antibody

背景资料

This gene encodes a member of the tumor necrosis factor (TNF) cytokine family which is a ligand for osteoprotegerin and functions as a key factor for osteoclast differentiation and activation. This protein was shown to be a dentritic cell survival factor and is involved in the regulation of T cell-dependent immune response. T cell activation was reported to induce expression of this gene and lead to an increase of osteoclastogenesis and bone loss. This protein was shown to activate antiapoptotic kinase AKT/PKB through a signaling complex involving SRC kinase and tumor necrosis factor receptor-associated factor (TRAF) 6, which indicated this protein may have a role in the regulation of cell apoptosis. Targeted disruption of the related gene in mice led to severe osteopetrosis and a lack of osteoclasts. The deficient mice exhibited defects in early differentiation of T and B lymphocytes, and failed to form lobulo-alveolar mammary structures during pregnancy. Two alternatively spliced transcript variants have been found.
Anti-TNFSF11 Polyclonal Antibody;抗体

公司简介

北京索莱宝科技有限公司是一家集研发、生产、销售、服务于一体的高科技生物企业。技术推广;技术转让;技术咨询;技术服务;生物试剂技术开发;销售生物试剂盒、实验室专用化学试剂、实验室专用设备、办公用品、化工产品(不含危险化学品)、计算机软件及辅助设备;货物进出口、技术进出口、代理进出口;委托加工生产生物制品、生化制品、化工产品(不含危险化学品);生产生物试剂盒;批发第一类医疗器械、第二类医疗器械;批发第三类医疗器械。

成立日期 (20年)
注册资本 1000万元
员工人数 50-100人
年营业额 ¥ 500万-1000万
经营模式 贸易,工厂,试剂
主营行业 分析化学,生物化工,化学试剂,医药原料,仪器耗材

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