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网站主页 ANTI-TAB1(N-TERM) MONOCLONAL ANTIBODY Anti-TAB1(N-term) Monoclonal Antibody
  • Anti-TAB1(N-term) Monoclonal Antibody

Anti-TAB1(N-term) Monoclonal Antibody

Anti-TAB1(N-term) Monoclonal Antibody
960.00 50ul 起订
1600.00 100ul 起订
北京 更新日期:2024-08-09

北京索莱宝科技有限公司

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联系人:索莱宝
电话:010-50973130拨打
手机:4009686088 拨打
邮箱:3193328036@qq.com

产品详情:

中文名称:
Anti-TAB1(N-term) Monoclonal Antibody
英文名称:
Anti-TAB1(N-term) Monoclonal Antibody
Gene ID:
10454
Public Immunogen Range:
Purified recombinant human TAB1(N-terminus) protein fragments expressed in E.coli.
Subcellular Locations:
Cytoplasm Nucleus
Swiss Prot:
Q15750
保存:
Store at -20°C. Avoid freeze / thaw cycles.
别名:
TAB 1;TAK1;TGF beta activated kinase 1 binding protein 1;MAP3K7IP 1
产品编号:
K001402M
储存液:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法:
Affinity purification
蛋白分子量:
55kDa
交叉反应:
Human
克隆号:
3D10-G10-B6
克隆类型:
Monoclonal Antibody
免疫原:
Purified recombinant human TAB1(N-terminus) protein fragments expressed in E.coli.
宿主:
Mouse
稀释比例:
WB 1:1000.
性状:
液体
亚型:
unknown
应用:
WB
英文名称:
Anti-TAB1(N-term) Monoclonal Antibody

背景资料

The protein encoded by this gene was identified as a regulator of the MAP kinase kinase kinase MAP3K7/TAK1, which is known to mediate various intracellular signaling pathways, such as those induced by TGF beta, interleukin 1, and WNT-1. This protein interacts and thus activates TAK1 kinase. It has been shown that the C-terminal portion of this protein is sufficient for binding and activation of TAK1, while a portion of the N-terminus acts as a dominant-negative inhibitor of TGF beta, suggesting that this protein may function as a mediator between TGF beta receptors and TAK1. This protein can also interact with and activate the mitogen-activated protein kinase 14 (MAPK14/p38alpha), and thus represents an alternative activation pathway, in addition to the MAPKK pathways, which contributes to the biological responses of MAPK14 to various stimuli. Alternatively spliced transcript variants encoding distinct isoforms have been reported
Anti-TAB1(N-term) Monoclonal Antibody;抗体

公司简介

北京索莱宝科技有限公司是一家集研发、生产、销售、服务于一体的高科技生物企业。技术推广;技术转让;技术咨询;技术服务;生物试剂技术开发;销售生物试剂盒、实验室专用化学试剂、实验室专用设备、办公用品、化工产品(不含危险化学品)、计算机软件及辅助设备;货物进出口、技术进出口、代理进出口;委托加工生产生物制品、生化制品、化工产品(不含危险化学品);生产生物试剂盒;批发第一类医疗器械、第二类医疗器械;批发第三类医疗器械。

成立日期 (20年)
注册资本 1000万元
员工人数 50-100人
年营业额 ¥ 500万-1000万
经营模式 贸易,工厂,试剂
主营行业 分析化学,生物化工,化学试剂,医药原料,仪器耗材

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