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  • Anti-SIGLEC12 Polyclonal Antibody

Anti-SIGLEC12 Polyclonal Antibody

Anti-SIGLEC12 Polyclonal Antibody
1600.00 100ul 起订
960.00 50ul 起订
北京 更新日期:2024-07-19

北京索莱宝科技有限公司

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联系人:索莱宝
电话:010-50973130拨打
手机:4009686088 拨打
邮箱:3193328036@qq.com

产品详情:

中文名称:
Anti-SIGLEC12 Polyclonal Antibody
英文名称:
Anti-SIGLEC12 Polyclonal Antibody
Gene ID:
89858
Public Immunogen Range:
Recombinant protein of human SIGLEC12
Subcellular Locations:
Membrane Single-pass type I membrane protein
Swiss Prot:
Q96PQ1
保存:
Store at -20°C. Avoid freeze / thaw cycles.
别名:
S2V;SIGLECL1;SLG;Siglec-XII
产品编号:
K005892P
储存液:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法:
Affinity purification
蛋白分子量:
65kDa
交叉反应:
Mouse
克隆类型:
Polyclonal Antibody
免疫原:
Recombinant protein of human SIGLEC12
宿主:
Rabbit
稀释比例:
WB 1:500-2000.
性状:
液体
亚型:
IgG
应用:
WB
英文名称:
Anti-SIGLEC12 Polyclonal Antibody

背景资料

Sialic acid-binding immunoglobulin-like lectins (SIGLECs) are a family of cell surface proteins belonging to the immunoglobulin superfamily. They mediate protein-carbohydrate interactions by selectively binding to different sialic acid moieties present on glycolipids and glycoproteins. This gene encodes a member of the SIGLEC3-like subfamily of SIGLECs. Members of this subfamily are characterized by an extracellular V-set immunoglobulin-like domain followed by two C2-set immunoglobulin-like domains, and the cytoplasmic tyrosine-based motifs ITIM and SLAM-like. The encoded protein, upon tyrosine phosphorylation, has been shown to recruit the Src homology 2 domain-containing protein-tyrosine phosphatases SHP1 and SHP2. It has been suggested that the protein is involved in the negative regulation of macrophage signaling by functioning as an inhibitory receptor. This gene is located in a cluster with other SIGLEC3-like genes on 19q13.4. Alternative splicing results in multiple transcript variants.
Anti-SIGLEC12 Polyclonal Antibody;抗体

公司简介

北京索莱宝科技有限公司是一家集研发、生产、销售、服务于一体的高科技生物企业。技术推广;技术转让;技术咨询;技术服务;生物试剂技术开发;销售生物试剂盒、实验室专用化学试剂、实验室专用设备、办公用品、化工产品(不含危险化学品)、计算机软件及辅助设备;货物进出口、技术进出口、代理进出口;委托加工生产生物制品、生化制品、化工产品(不含危险化学品);生产生物试剂盒;批发第一类医疗器械、第二类医疗器械;批发第三类医疗器械。

成立日期 (20年)
注册资本 1000万元
员工人数 50-100人
年营业额 ¥ 500万-1000万
经营模式 贸易,工厂,试剂
主营行业 分析化学,生物化工,化学试剂,医药原料,仪器耗材

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