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  • Anti-PRKG1 Polyclonal Antibody

Anti-PRKG1 Polyclonal Antibody

Anti-PRKG1 Polyclonal Antibody
960.00 50ul 起订
1600.00 100ul 起订
北京 更新日期:2024-08-09

北京索莱宝科技有限公司

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联系人:索莱宝
电话:010-50973130拨打
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邮箱:3193328036@qq.com

产品详情:

中文名称:
Anti-PRKG1 Polyclonal Antibody
英文名称:
Anti-PRKG1 Polyclonal Antibody
Gene ID:
5592
Public Immunogen Range:
Recombinant protein of human PRKG1
Subcellular Locations:
Cytoplasm
Swiss Prot:
Q13976
保存:
Store at -20°C. Avoid freeze / thaw cycles.
别名:
AAT8;PKG;PRKG1B;PRKGR1B;cGK;cGK 1;cGK1;cGKI;cGKI-BETA;cGKI-alpha
产品编号:
K003422P
储存液:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法:
Affinity purification
蛋白分子量:
76kDa
交叉反应:
Human Mouse
克隆类型:
Polyclonal Antibody
免疫原:
Recombinant protein of human PRKG1
宿主:
Rabbit
稀释比例:
WB 1:500-2000. IHC 1:50-200.
性状:
液体
亚型:
IgG
应用:
WB IHC
英文名称:
Anti-PRKG1 Polyclonal Antibody

背景资料

Mammals have three different isoforms of cyclic GMP-dependent protein kinase (Ialpha, Ibeta, and II). These PRKG isoforms act as key mediators of the nitric oxide/cGMP signaling pathway and are important components of many signal transduction processes in diverse cell types. This PRKG1 gene on human chromosome 10 encodes the soluble Ialpha and Ibeta isoforms of PRKG by alternative transcript splicing. A separate gene on human chromosome 4, PRKG2, encodes the membrane-bound PRKG isoform II. The PRKG1 proteins play a central role in regulating cardiovascular and neuronal functions in addition to relaxing smooth muscle tone, preventing platelet aggregation, and modulating cell growth. This gene is most strongly expressed in all types of smooth muscle, platelets, cerebellar Purkinje cells, hippocampal neurons, and the lateral amygdala. Isoforms Ialpha and Ibeta have identical cGMP-binding and catalytic domains but differ in their leucine/isoleucine zipper and autoinhibitory sequences and therefore differ in their dimerization substrates and kinase enzyme activity.
Anti-PRKG1 Polyclonal Antibody;抗体

公司简介

北京索莱宝科技有限公司是一家集研发、生产、销售、服务于一体的高科技生物企业。技术推广;技术转让;技术咨询;技术服务;生物试剂技术开发;销售生物试剂盒、实验室专用化学试剂、实验室专用设备、办公用品、化工产品(不含危险化学品)、计算机软件及辅助设备;货物进出口、技术进出口、代理进出口;委托加工生产生物制品、生化制品、化工产品(不含危险化学品);生产生物试剂盒;批发第一类医疗器械、第二类医疗器械;批发第三类医疗器械。

成立日期 (20年)
注册资本 1000万元
员工人数 50-100人
年营业额 ¥ 500万-1000万
经营模式 贸易,工厂,试剂
主营行业 分析化学,生物化工,化学试剂,医药原料,仪器耗材

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