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  • Anti-PPP3CA Polyclonal Antibody

Anti-PPP3CA Polyclonal Antibody

Anti-PPP3CA Polyclonal Antibody
1600.00 100ul 起订
960.00 50ul 起订
北京 更新日期:2025-01-15

北京索莱宝科技有限公司

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产品详情:

中文名称:
Anti-PPP3CA Polyclonal Antibody
英文名称:
Anti-PPP3CA Polyclonal Antibody
Subcellular Locations:
Cytoplasm
Swiss Prot:
Q08209
保存:
Store at -20°C. Avoid freeze / thaw cycles.
别名:
CALN; CALNA; CALNA1; CCN1; CNA1; PPP2B; protein phosphatase 3 catalytic subunit alpha
产品编号:
K107562P
储存液:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法:
Affinity purification
蛋白分子量:
32/58kDa
交叉反应:
Human Mouse Rat Cow
克隆类型:
Polyclonal Antibody
免疫原:
A synthetic peptide of human PPP3CA
宿主:
Rabbit
稀释比例:
IHC 1:100-300.
亚型:
IgG
应用:
IHC
英文名称:
Anti-PPP3CA Polyclonal Antibody

背景资料

Calcium-dependent, calmodulin-stimulated protein phosphatase which plays an essential role in the transduction of intracellular Ca2+-mediated signals (PubMed:15671020, PubMed:18838687, PubMed:19154138, PubMed:23468591). Many of the substrates contain a PxIxIT motif and/or a LxVP motif (PubMed:17498738, PubMed:17502104, PubMed:23468591, PubMed:27974827, PubMed:22343722). In response to increased Ca2+?levels, dephosphorylates and activates phosphatase SSH1 which results in cofilin dephosphorylation (PubMed:15671020). In response to increased Ca2+?levels following mitochondrial depolarization, dephosphorylates DNM1L inducing DNM1L translocation to the mitochondrion (PubMed:18838687). Dephosphorylates heat shock protein HSPB1 (By similarity). Dephosphorylates and activates transcription factor NFATC1 (PubMed:19154138). In response to increased Ca2+?levels, regulates NFAT-mediated transcription probably by dephosphorylating NFAT and promoting its nuclear translocation (PubMed:26248042). Dephosphorylates and inactivates transcription factor ELK1 (PubMed:19154138). Dephosphorylates DARPP32 (PubMed:19154138).
Anti-PPP3CA Polyclonal Antibody;抗体

公司简介

北京索莱宝科技有限公司是一家集研发、生产、销售、服务于一体的高科技生物企业。技术推广;技术转让;技术咨询;技术服务;生物试剂技术开发;销售生物试剂盒、实验室专用化学试剂、实验室专用设备、办公用品、化工产品(不含危险化学品)、计算机软件及辅助设备;货物进出口、技术进出口、代理进出口;委托加工生产生物制品、生化制品、化工产品(不含危险化学品);生产生物试剂盒;批发第一类医疗器械、第二类医疗器械;批发第三类医疗器械。

成立日期 (21年)
注册资本 1000万元
员工人数 50-100人
年营业额 ¥ 500万-1000万
经营模式 贸易,工厂,试剂
主营行业 分析化学,生物化工,化学试剂,医药原料,仪器耗材

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