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  • Anti-Phospho-RAF1-S259 Polyclonal Antibody

Anti-Phospho-RAF1-S259 Polyclonal Antibody

Anti-Phospho-RAF1-S259 Polyclonal Antibody
1600.00 100ul 起订
960.00 50ul 起订
北京 更新日期:2024-06-21

北京索莱宝科技有限公司

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联系人:索莱宝
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产品详情:

中文名称:
Anti-Phospho-RAF1-S259 Polyclonal Antibody
英文名称:
Anti-Phospho-RAF1-S259 Polyclonal Antibody
Gene ID:
5894
Public Immunogen Range:
A phospho specific peptide corresponding to residues surrounding S259 of human RAF1
Subcellular Locations:
Cell membrane Cytoplasm Mitochondrion Nucleus
Swiss Prot:
P04049
保存:
Store at -20°C. Avoid freeze / thaw cycles.
别名:
CMD1NN;CRAF;NS5;Raf-1;c-Raf
产品编号:
K006222P
储存液:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法:
Affinity purification
蛋白分子量:
73kDa
交叉反应:
Human Mouse
克隆类型:
Polyclonal Antibody
免疫原:
A phospho specific peptide corresponding to residues surrounding S259 of human RAF1
宿主:
Rabbit
稀释比例:
WB 1:500-2000. IP 1:50-100.
性状:
液体
亚型:
IgG
应用:
WB IP
英文名称:
Anti-Phospho-RAF1-S259 Polyclonal Antibody

背景资料

This gene is the cellular homolog of viral raf gene (v-raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine/threonine specific protein kinases, ERK1 and ERK2. Activated ERKs are pleiotropic effectors of cell physiology and play an important role in the control of gene expression involved in the cell division cycle, apoptosis, cell differentiation and cell migration. Mutations in this gene are associated with Noonan syndrome 5 and LEOPARD syndrome 2.
Anti-Phospho-RAF1-S259 Polyclonal Antibody;抗体

公司简介

北京索莱宝科技有限公司是一家集研发、生产、销售、服务于一体的高科技生物企业。技术推广;技术转让;技术咨询;技术服务;生物试剂技术开发;销售生物试剂盒、实验室专用化学试剂、实验室专用设备、办公用品、化工产品(不含危险化学品)、计算机软件及辅助设备;货物进出口、技术进出口、代理进出口;委托加工生产生物制品、生化制品、化工产品(不含危险化学品);生产生物试剂盒;批发第一类医疗器械、第二类医疗器械;批发第三类医疗器械。

成立日期 (20年)
注册资本 1000万元
员工人数 50-100人
年营业额 ¥ 500万-1000万
经营模式 贸易,工厂,试剂
主营行业 分析化学,生物化工,化学试剂,医药原料,仪器耗材

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