基本信息 产品详情 公司简介 推荐产品
网站主页 ANTI-FAS(C-TERM) MONOCLONAL ANTIBODY Anti-FAS(C-term) Monoclonal Antibody
  • Anti-FAS(C-term) Monoclonal Antibody

Anti-FAS(C-term) Monoclonal Antibody

Anti-FAS(C-term) Monoclonal Antibody
960.00 50ul 起订
1600.00 100ul 起订
北京 更新日期:2024-11-05

北京索莱宝科技有限公司

VIP9年
联系人:索莱宝
电话:010-50973130拨打
手机:4009686088 拨打
邮箱:3193328036@qq.com

产品详情:

中文名称:
Anti-FAS(C-term) Monoclonal Antibody
英文名称:
Anti-FAS(C-term) Monoclonal Antibody
Gene ID:
355
Public Immunogen Range:
Purified recombinant human FAS (C-terminus) protein fragments expressed in E.coli.
Subcellular Locations:
Cell membrane Secreted Single-pass type I membrane protein
Swiss Prot:
P25445
保存:
Store at -20°C. Avoid freeze / thaw cycles.
别名:
ALPS1A;APO-1;APT1;CD95;FAS1;FASTM;TNFRSF6
产品编号:
K000037M
储存液:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法:
Affinity purification
蛋白分子量:
38kDa
交叉反应:
Human
克隆号:
4C3-G7-B7-H5
克隆类型:
Monoclonal Antibody
免疫原:
Purified recombinant human FAS (C-terminus) protein fragments expressed in E.coli.
宿主:
Mouse
稀释比例:
WB 1:1000.
性状:
液体
亚型:
IgG1
应用:
WB
英文名称:
Anti-FAS(C-term) Monoclonal Antibody

背景资料

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains a death domain. It has been shown to play a central role in the physiological regulation of programmed cell death, and has been implicated in the pathogenesis of various malignancies and diseases of the immune system. The interaction of this receptor with its ligand allows the formation of a death-inducing signaling complex that includes Fas-associated death domain protein (FADD), caspase 8, and caspase 10. The autoproteolytic processing of the caspases in the complex triggers a downstream caspase cascade, and leads to apoptosis. This receptor has been also shown to activate NF-kappaB, MAPK3/ERK1, and MAPK8/JNK, and is found to be involved in transducing the proliferating signals in normal diploid fibroblast and T cells. At least eight alternatively spliced transcript variants have been described, some of which are candidates for nonsense-mediated decay (NMD). The isoforms lacking the transmembrane domain may negatively regulate the apoptosis mediated by the full length isoform.
Anti-FAS(C-term) Monoclonal Antibody;蛋白与免疫

公司简介

北京索莱宝科技有限公司是一家集研发、生产、销售、服务于一体的高科技生物企业。技术推广;技术转让;技术咨询;技术服务;生物试剂技术开发;销售生物试剂盒、实验室专用化学试剂、实验室专用设备、办公用品、化工产品(不含危险化学品)、计算机软件及辅助设备;货物进出口、技术进出口、代理进出口;委托加工生产生物制品、生化制品、化工产品(不含危险化学品);生产生物试剂盒;批发第一类医疗器械、第二类医疗器械;批发第三类医疗器械。

成立日期 (21年)
注册资本 1000万元
员工人数 50-100人
年营业额 ¥ 500万-1000万
经营模式 贸易,工厂,试剂
主营行业 分析化学,生物化工,化学试剂,医药原料,仪器耗材

Anti-FAS(C-term) Monoclonal Antibody相关厂家报价

内容声明
拨打电话 立即询价