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  • Anti-FBXW7 Polyclonal Antibody

Anti-FBXW7 Polyclonal Antibody

Anti-FBXW7 Polyclonal Antibody
1600.00 100ul 起订
960.00 50ul 起订
北京 更新日期:2024-08-23

北京索莱宝科技有限公司

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产品详情:

中文名称:
Anti-FBXW7 Polyclonal Antibody
英文名称:
Anti-FBXW7 Polyclonal Antibody
Gene ID:
55294
Public Immunogen Range:
Recombinant protein of human FBXW7
Subcellular Locations:
Cytoplasm Nucleus nucleolus nucleoplasm
Swiss Prot:
Q969H0
保存:
Store at -20°C. Avoid freeze / thaw cycles.
别名:
AGO;CDC4;FBW6;FBW7;FBX30;FBXO30;FBXW6;SEL-10;SEL10;hAgo;hCdc4
产品编号:
K004271P
储存液:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法:
Affinity purification
蛋白分子量:
80kDa
交叉反应:
Human Mouse Rat
克隆类型:
Polyclonal Antibody
免疫原:
Recombinant protein of human FBXW7
宿主:
Rabbit
稀释比例:
WB 1:500-2000. IHC 1:50-200. IF 1:50-200.
性状:
液体
亚型:
IgG
应用:
WB IHC IF
英文名称:
Anti-FBXW7 Polyclonal Antibody

背景资料

This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene was previously referred to as FBX30, and belongs to the Fbws class; in addition to an F-box, this protein contains 7 tandem WD40 repeats. This protein binds directly to cyclin E and probably targets cyclin E for ubiquitin-mediated degradation. Mutations in this gene are detected in ovarian and breast cancer cell lines, implicating the gene's potential role in the pathogenesis of human cancers. Multiple transcript variants encoding different isoforms have been found for this gene.
Anti-FBXW7 Polyclonal Antibody;抗体

公司简介

北京索莱宝科技有限公司是一家集研发、生产、销售、服务于一体的高科技生物企业。技术推广;技术转让;技术咨询;技术服务;生物试剂技术开发;销售生物试剂盒、实验室专用化学试剂、实验室专用设备、办公用品、化工产品(不含危险化学品)、计算机软件及辅助设备;货物进出口、技术进出口、代理进出口;委托加工生产生物制品、生化制品、化工产品(不含危险化学品);生产生物试剂盒;批发第一类医疗器械、第二类医疗器械;批发第三类医疗器械。

成立日期 (20年)
注册资本 1000万元
员工人数 50-100人
年营业额 ¥ 500万-1000万
经营模式 贸易,工厂,试剂
主营行业 分析化学,生物化工,化学试剂,医药原料,仪器耗材

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