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  • Anti-CALR Polyclonal Antibody

Anti-CALR Polyclonal Antibody

Anti-CALR Polyclonal Antibody
1600.00 100ul 起订
960.00 50ul 起订
北京 更新日期:2024-06-14

北京索莱宝科技有限公司

VIP9年
联系人:索莱宝
电话:010-50973130拨打
手机:4009686088 拨打
邮箱:3193328036@qq.com

产品详情:

中文名称:
Anti-CALR Polyclonal Antibody
英文名称:
Anti-CALR Polyclonal Antibody
Gene ID:
811
Public Immunogen Range:
Recombinant protein of human CALR
Swiss Prot:
P27797
保存:
Store at -20°C. Avoid freeze / thaw cycles.
别名:
CRT;HEL-S-99n;RO;SSA;cC1qR
产品编号:
K008162P
储存液:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法:
Affinity purification
蛋白分子量:
48kDa
克隆类型:
Polyclonal Antibody
免疫原:
Recombinant protein of human CALR
宿主:
Rabbit
稀释比例:
WB 1:1000-5000. IHC 1:50-200.
性状:
液体
亚型:
IgG
应用:
WB IHC
英文名称:
Anti-CALR Polyclonal Antibody

Subcellular Locations

Cell surface Cytoplasm Endoplasmic reticulum lumen Sarcoplasmic reticulum lumen Secreted cytosol extracellular matrix extracellular space

背景资料

Calreticulin is a multifunctional protein that acts as a major Ca(2+)-binding (storage) protein in the lumen of the endoplasmic reticulum. It is also found in the nucleus, suggesting that it may have a role in transcription regulation. Calreticulin binds to the synthetic peptide KLGFFKR, which is almost identical to an amino acid sequence in the DNA-binding domain of the superfamily of nuclear receptors. Calreticulin binds to antibodies in certain sera of systemic lupus and Sjogren patients which contain anti-Ro/SSA antibodies, it is highly conserved among species, and it is located in the endoplasmic and sarcoplasmic reticulum where it may bind calcium. The amino terminus of calreticulin interacts with the DNA-binding domain of the glucocorticoid receptor and prevents the receptor from binding to its specific glucocorticoid response element.
Anti-CALR Polyclonal Antibody;抗体

公司简介

北京索莱宝科技有限公司是一家集研发、生产、销售、服务于一体的高科技生物企业。技术推广;技术转让;技术咨询;技术服务;生物试剂技术开发;销售生物试剂盒、实验室专用化学试剂、实验室专用设备、办公用品、化工产品(不含危险化学品)、计算机软件及辅助设备;货物进出口、技术进出口、代理进出口;委托加工生产生物制品、生化制品、化工产品(不含危险化学品);生产生物试剂盒;批发第一类医疗器械、第二类医疗器械;批发第三类医疗器械。

成立日期 (20年)
注册资本 1000万元
员工人数 50-100人
年营业额 ¥ 500万-1000万
经营模式 贸易,工厂,试剂
主营行业 分析化学,生物化工,化学试剂,医药原料,仪器耗材

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