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Anti-DDB1 Polyclonal Antibody

Anti-DDB1 Polyclonal Antibody
1600.00 100ul 起订
960.00 50ul 起订
北京 更新日期:2024-11-29

北京索莱宝科技有限公司

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联系人:索莱宝
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产品详情:

中文名称:
Anti-DDB1 Polyclonal Antibody
英文名称:
Anti-DDB1 Polyclonal Antibody
Gene ID:
1642
Public Immunogen Range:
A synthetic peptide of human DDB1
Subcellular Locations:
Cytoplasm Nucleus
Swiss Prot:
Q16531
保存:
Store at -20°C. Avoid freeze / thaw cycles.
别名:
DDBA;UV-DDB1;XAP1;XPCE;XPE;XPE-BF
产品编号:
K003523P
储存液:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法:
Affinity purification
蛋白分子量:
127kDa
交叉反应:
Human Mouse Rat
克隆类型:
Polyclonal Antibody
免疫原:
A synthetic peptide of human DDB1
宿主:
Rabbit
稀释比例:
WB 1:500-1000. IHC 1:50-100.
性状:
液体
亚型:
IgG
应用:
WB IHC
英文名称:
Anti-DDB1 Polyclonal Antibody

背景资料

The protein encoded by this gene is the large subunit (p127) of the heterodimeric DNA damage-binding (DDB) complex while another protein (p48) forms the small subunit. This protein complex functions in nucleotide-excision repair and binds to DNA following UV damage. Defective activity of this complex causes the repair defect in patients with xeroderma pigmentosum complementation group E (XPE) - an autosomal recessive disorder characterized by photosensitivity and early onset of carcinomas. However, it remains for mutation analysis to demonstrate whether the defect in XPE patients is in this gene or the gene encoding the small subunit. In addition, Best vitelliform mascular dystrophy is mapped to the same region as this gene on 11q, but no sequence alternations of this gene are demonstrated in Best disease patients. The protein encoded by this gene also functions as an adaptor molecule for the cullin 4 (CUL4) ubiquitin E3 ligase complex by facilitating the binding of substrates to this complex and the ubiquitination of proteins.
Anti-DDB1 Polyclonal Antibody;抗体

公司简介

北京索莱宝科技有限公司是一家集研发、生产、销售、服务于一体的高科技生物企业。技术推广;技术转让;技术咨询;技术服务;生物试剂技术开发;销售生物试剂盒、实验室专用化学试剂、实验室专用设备、办公用品、化工产品(不含危险化学品)、计算机软件及辅助设备;货物进出口、技术进出口、代理进出口;委托加工生产生物制品、生化制品、化工产品(不含危险化学品);生产生物试剂盒;批发第一类医疗器械、第二类医疗器械;批发第三类医疗器械。

成立日期 (21年)
注册资本 1000万元
员工人数 50-100人
年营业额 ¥ 500万-1000万
经营模式 贸易,工厂,试剂
主营行业 分析化学,生物化工,化学试剂,医药原料,仪器耗材

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