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  • Anti-CDKN1A Polyclonal Antibody

Anti-CDKN1A Polyclonal Antibody

Anti-CDKN1A Polyclonal Antibody
960.00 50ul 起订
1600.00 100ul 起订
北京 更新日期:2024-11-22

北京索莱宝科技有限公司

VIP9年
联系人:索莱宝
电话:010-50973130拨打
手机:4009686088 拨打
邮箱:3193328036@qq.com

产品详情:

中文名称:
Anti-CDKN1A Polyclonal Antibody
英文名称:
Anti-CDKN1A Polyclonal Antibody
Gene ID:
1026
Public Immunogen Range:
Recombinant protein of human CDKN1A
Subcellular Locations:
Cytoplasm Nucleus
Swiss Prot:
P38936
保存:
Store at -20°C. Avoid freeze / thaw cycles.
别名:
P21;CIP1;SDI1;WAF1;CAP20;CDKN1;MDA-6;p21CIP1
产品编号:
K008127P
储存液:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法:
Affinity purification
蛋白分子量:
18kDa
交叉反应:
Human
克隆类型:
Polyclonal Antibody
免疫原:
Recombinant protein of human CDKN1A
宿主:
Rabbit
稀释比例:
IHC 1:25-100.
性状:
液体
亚型:
IgG
应用:
IHC
英文名称:
Anti-CDKN1A Polyclonal Antibody

背景资料

This gene encodes a potent cyclin-dependent kinase inhibitor. The encoded protein binds to and inhibits the activity of cyclin-cyclin-dependent kinase2 or -cyclin-dependent kinase4 complexes, and thus functions as a regulator of cell cycle progression at G1. The expression of this gene is tightly controlled by the tumor suppressor protein p53, through which this protein mediates the p53-dependent cell cycle G1 phase arrest in response to a variety of stress stimuli. This protein can interact with proliferating cell nuclear antigen, a DNA polymerase accessory factor, and plays a regulatory role in S phase DNA replication and DNA damage repair. This protein was reported to be specifically cleaved by CASP3-like caspases, which thus leads to a dramatic activation of cyclin-dependent kinase2, and may be instrumental in the execution of apoptosis following caspase activation. Mice that lack this gene have the ability to regenerate damaged or missing tissue. Multiple alternatively spliced variants have been found for this gene.
Anti-CDKN1A Polyclonal Antibody;抗体

公司简介

北京索莱宝科技有限公司是一家集研发、生产、销售、服务于一体的高科技生物企业。技术推广;技术转让;技术咨询;技术服务;生物试剂技术开发;销售生物试剂盒、实验室专用化学试剂、实验室专用设备、办公用品、化工产品(不含危险化学品)、计算机软件及辅助设备;货物进出口、技术进出口、代理进出口;委托加工生产生物制品、生化制品、化工产品(不含危险化学品);生产生物试剂盒;批发第一类医疗器械、第二类医疗器械;批发第三类医疗器械。

成立日期 (21年)
注册资本 1000万元
员工人数 50-100人
年营业额 ¥ 500万-1000万
经营模式 贸易,工厂,试剂
主营行业 分析化学,生物化工,化学试剂,医药原料,仪器耗材

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