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网站主页 ANTI-DLAT MONOCLONAL ANTIBODY Anti-DLAT Monoclonal Antibody
  • Anti-DLAT Monoclonal Antibody

Anti-DLAT Monoclonal Antibody

Anti-DLAT Monoclonal Antibody
960.00 50ul 起订
1600.00 100ul 起订
北京 更新日期:2025-01-22

北京索莱宝科技有限公司

VIP9年
联系人:索莱宝
电话:010-50973130拨打
手机:4009686088 拨打
邮箱:3193328036@qq.com

产品详情:

中文名称:
Anti-DLAT Monoclonal Antibody
英文名称:
Anti-DLAT Monoclonal Antibody
Gene ID:
1737
Subcellular Locations:
Mitochondrion matrix
Swiss Prot:
P10515
保存:
Store at -20°C. Avoid freeze / thaw cycles.
别名:
DLTA;PDC-E2;PDCE2
产品编号:
K000072M
储存液:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法:
Affinity purification
蛋白分子量:
69kDa
克隆号:
4A4-B6-C10
克隆类型:
Monoclonal Antibody
免疫原:
Purified recombinant human DLAT protein fragments expressed in E.coli.
宿主:
Mouse
稀释比例:
WB 1:1000. ICC 1:300.
性状:
液体
亚型:
IgG1
应用:
WB ICC IP
英文名称:
Anti-DLAT Monoclonal Antibody

背景资料

This gene encodes component E2 of the multi-enzyme pyruvate dehydrogenase complex (PDC). PDC resides in the inner mitochondrial membrane and catalyzes the conversion of pyruvate to acetyl coenzyme A. The protein product of this gene, dihydrolipoamide acetyltransferase, accepts acetyl groups formed by the oxidative decarboxylation of pyruvate and transfers them to coenzyme A. Dihydrolipoamide acetyltransferase is the antigen for antimitochondrial antibodies. These autoantibodies are present in nearly 95% of patients with the autoimmune liver disease primary biliary cirrhosis (PBC). In PBC, activated T lymphocytes attack and destroy epithelial cells in the bile duct where this protein is abnormally distributed and overexpressed. PBC enventually leads to cirrhosis and liver failure. Mutations in this gene are also a cause of pyruvate dehydrogenase E2 deficiency which causes primary lactic acidosis in infancy and early childhood
Anti-DLAT Monoclonal Antibody;抗体

公司简介

北京索莱宝科技有限公司是一家集研发、生产、销售、服务于一体的高科技生物企业。技术推广;技术转让;技术咨询;技术服务;生物试剂技术开发;销售生物试剂盒、实验室专用化学试剂、实验室专用设备、办公用品、化工产品(不含危险化学品)、计算机软件及辅助设备;货物进出口、技术进出口、代理进出口;委托加工生产生物制品、生化制品、化工产品(不含危险化学品);生产生物试剂盒;批发第一类医疗器械、第二类医疗器械;批发第三类医疗器械。

成立日期 (21年)
注册资本 1000万元
员工人数 50-100人
年营业额 ¥ 500万-1000万
经营模式 贸易,工厂,试剂
主营行业 分析化学,生物化工,化学试剂,医药原料,仪器耗材

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