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  • Anti-CASP8 Polyclonal Antibody

Anti-CASP8 Polyclonal Antibody

Anti-CASP8 Polyclonal Antibody
960.00 50ul 起订
1600.00 100ul 起订
北京 更新日期:2024-08-09

北京索莱宝科技有限公司

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联系人:索莱宝
电话:010-50973130拨打
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邮箱:3193328036@qq.com

产品详情:

中文名称:
Anti-CASP8 Polyclonal Antibody
英文名称:
Anti-CASP8 Polyclonal Antibody
Gene ID:
841
Public Immunogen Range:
Recombinant protein of human CASP8
Subcellular Locations:
Cytoplasm
Swiss Prot:
Q14790
保存:
Store at -20°C. Avoid freeze / thaw cycles.
别名:
ALPS2B;CAP4;Casp-8;FLICE;MACH;MCH5;Caspase 8
产品编号:
K002246P
储存液:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法:
Affinity purification
蛋白分子量:
55kDa/53kDa/45kDa/57kDa/27kDa/25kDa/32kDa/30kDa/61kDa
交叉反应:
Human
克隆类型:
Polyclonal Antibody
免疫原:
Recombinant protein of human CASP8
宿主:
Rabbit
稀释比例:
WB 1:500-1000. IF 1:50-100.
性状:
液体
亚型:
IgG
应用:
WB IF
英文名称:
Anti-CASP8 Polyclonal Antibody

背景资料

This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain, a large protease subunit, and a small protease subunit. Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the large and small subunits. This protein is involved in the programmed cell death induced by Fas and various apoptotic stimuli. The N-terminal FADD-like death effector domain of this protein suggests that it may interact with Fas-interacting protein FADD. This protein was detected in the insoluble fraction of the affected brain region from Huntington disease patients but not in those from normal controls, which implicated the role in neurodegenerative diseases. Many alternatively spliced transcript variants encoding different isoforms have been described, although not all variants have had their full-length sequences determined.
Anti-CASP8 Polyclonal Antibody;抗体

公司简介

北京索莱宝科技有限公司是一家集研发、生产、销售、服务于一体的高科技生物企业。技术推广;技术转让;技术咨询;技术服务;生物试剂技术开发;销售生物试剂盒、实验室专用化学试剂、实验室专用设备、办公用品、化工产品(不含危险化学品)、计算机软件及辅助设备;货物进出口、技术进出口、代理进出口;委托加工生产生物制品、生化制品、化工产品(不含危险化学品);生产生物试剂盒;批发第一类医疗器械、第二类医疗器械;批发第三类医疗器械。

成立日期 (20年)
注册资本 1000万元
员工人数 50-100人
年营业额 ¥ 500万-1000万
经营模式 贸易,工厂,试剂
主营行业 分析化学,生物化工,化学试剂,医药原料,仪器耗材

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