BMS-663068 Tris

产品说明

HIV-1附着抑制剂

该产品包含在以下化合物库中:

质量控制

• 纯度 = 98.00%

化学性质

CAS号	864953-39-9
别名	BMS663068 (Tris);BMS 663068 (Tris)
分子式	C29H37N8O11P	分子量	704.62
溶解性	DMSO	储存条件	Store at -20°

 

实验操作

细胞实验[2]：
细胞系
溶解方法
反应时间
应用
动物实验[3]：
动物模型
剂量
注意事项
References:

产品描述

BMS-663068 is an HIV-1 attachment inhibitor in development for the treatment of HIV-1 infection. BMS-663068 is a prodrug for BMS-626529 which binds to the viral envelope glycoprotein gp120 and interferes with attachment of the virus to the cellular CD4 receptor. Administration of BMS-663068 for 8 days with or without ritonavir resulted in substantial declines in plasma HIV-1 RNA levels and was generally well tolerated. Longer-term clinical trials of BMS-663068 as part of combination antiretroviral therapy are warranted.