17-phenyl trinor Prostaglandin E2

17-phenyl trinor PGE2 is a synthetic analog of PGE2. It is an EP1 and EP3 receptor agonist.{3318,1025} 17-phenyl trinor PGE2 is an EP1 and EP3 receptor agonist.1,2 It causes contraction of the guinea pig ileum at a concentration of 11 µM.{3318} It is slightly less potent than PGE2 in stimulating gerbil colon and rat uterus.{1025} With an ED50 value of 350 µg/kg, 17-phenyl trinor PGE2 is 4.4 times more potent than PGE2 as an antifertility agent in hamsters.{1025}