产品编号 |
产品名称 |
产品包装 |
产品价格 |
P6128-10μg |
Recombinant Murine HB-EGF |
10μg |
464.00元 |
Species
|
Gene ID
|
Accession
|
Source
|
Length
|
MW
|
Tag
|
Mouse
|
15200
|
Q06186
|
E. coli
|
86aa
|
9.8kDa
|
-
|
About this Antibody
|
Name
|
Recombinant Murine HB-EGF (Recombinant Murine Heparin-binding EGF-like Growth Factor; rMuHB-EGF);Recombinant Mouse HB-EGF ; 重组小鼠肝素结合表皮生长因子样生长因子
|
Synonyms
|
Dtr; Dts; Hegfl; diphtheria toxin receptor (heparin-binding epidermal growth factor-like growthfactor); DTRHEGFLdiphtheria toxin receptor (heparin-binding EGF-like growth factor); DTS; DTSF; heparin-binding EGF-like growth factor; heparin-binding epidermal growth factor; proheparin-binding EGF-like growth factor
|
Purity
|
>97% by SDS-PAGE and HPLC analyses.
|
Biological Activity
|
Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using murine Balb/c 3T3 cells is less than 1ng/ml, corresponding to a specific activity of >1.0×106IU/mg.
|
Physical Appearance
|
Sterile Filtered White lyophilized (freeze-dried) powder.
|
Formulation
|
Lyophilized from a 0.2μm filtered concentrated solution in 10mM PB, 500mM NaCl, pH7.4.
|
Endotoxin
|
Less than 1EU/μg of rMuHB-EGF as determined by LAL method.
|
Reconstitution
|
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0mg/ml. Stock solutions should be apportioned into working aliquots and stored at ≤-20℃. Further dilutions should be made in appropriate buffered solutions.
|
Category
|
Cytokine
|
Background
|
Heparin-binding epidermal growth factor (HB-EGF)-like growth factor (EGF) is found in cerebral neurons. Its expression is increased after hypoxic or ischemic injury, which also stimulates neurogenesis. HB-EGF has been implicated as a participant in a variety of normal physiological processes such as blastocyst implantation and wound healing, and in pathological processes such as tumor growth, SMC hyperplasia and atherosclerosis. The protein is an 87 amino acid mitogenic and chemotactic glycoprotein containing an EGF-like domain with six conserved cysteine residues. Murine HB-EGF shares about 81%a.a. sequence identity with human HB-EGF.
|
Amino Acid Sequence
|
DLEGTDLNLF KVAFSSKPQG LATPSKERNG KKKKKGKGLG KKRDPCLRKY KDYCIHGECR YLQEFRTPSC KCLPGYHGHR CHGLTL
|
包装清单:
产品编号
|
产品名称
|
包装
|
P6128-10μg
|
Recombinant Murine HB-EGF
|
10μg
|
P6128-50μg
|
Recombinant Murine HB-EGF
|
50μg
|
P6128-100μg
|
Recombinant Murine HB-EGF
|
100μg
|
P6128-1mg
|
Recombinant Murine HB-EGF
|
1mg
|
-
|
说明书
|
1份
|
保存条件:
-20℃或更低温度保存,至少一年有效。由于蛋白的每次冻融均会引起部分失活,所以首次配制成相应浓度的储存液后(请根据产品简介中Reconstitution一栏的信息配制储存液),须分装后-20℃或更低温度冻存,以避免反复冻融。
注意事项:
由于有些塑料管壁对某些蛋白有较强的吸附作用,溶液中的蛋白很容易粘附在管壁上,并且粘附后的蛋白很难与管壁分离。而载体蛋白(Carrier protein,如0.1% BSA等)的主要作用是预先封闭塑料管壁上的蛋白结合位点,使细胞因子或重组蛋白不会粘附于管壁。所以一定要使用产品简介中Reconstitution一栏的信息配制储存液。
本产品仅限于专业人员的科学研究用,不得用于临床诊断或治疗,不得用于食品或药品,不得存放于普通住宅内。
为了您的安全和健康,请穿实验服并戴一次性手套操作。