N,N-二乙基烟酰胺（尼可刹米）

Introduction:

Chinese name:N, N-Diethylnicotinamide(Nikethamide)

English name:N,N-Diethylnicotinamide(Nikethamide) 

Molecular formula：C10H14N2O

Molecular weight:178.23

Melting point:23 °C(lit.)

Boiling point:296-300 °C(lit.)

Relative density:1.058-1.066（25/4℃）

Refractive index:n20/D 1.524(lit.)

Flash point:>230 °F

Shape:Liquid

pKa:pKa 3.46(H2O,t =20) (Uncertain)

Color:Clear colorless to yellow

CAS:59-26-7(CAS DataBase Reference)

EINECS：200-418-5

Related Categories:API;Small Molecular Inhibitors;Pharmaceutical API;NIKETHYL;-;Nitrogen cyclic compounds;Heterocyclic Compounds

Mol：59-26-7.mol

Purity: 99%

Indication:For central respiratory depression and respiratory depression caused by various reasons.It is a central stimulant and also used for intoxication of anesthetics and other central inhibitors.LD50 was 272 mg/kg by intraperitoneal injection in rats.

Adverse reactions:Common facial irritation, restlessness, convulsions, nausea and vomiting, etc.High doses can lead to elevated blood pressure, palpitations, sweating, facial flushing, vomiting, tremor, arrhythmia, convulsions, and even coma.

Taboo:Patients with hyperspasmia and convulsions.

Precautions:The action time is short and should be given at intervals depending on the condition.

Drug Interaction:Combined with other central stimulants, it has synergistic effect and can cause convulsions.

Packaging:25KG/Barrel

Note:Pharmaceutical Intermediates, Fine Chemicals, Chemical Reagents, Material Intermediates.