产品编号 |
产品名称 |
产品包装 |
产品价格 |
P5376-20μg |
Recombinant Human BCMA/TNFRSF17 |
20μg |
1152.00元 |
Species
|
Gene ID
|
Accession
|
Source
|
Length
|
MW
|
Tag
|
Human
|
608
|
Q02223
|
E. coli
|
50aa
|
5.4kDa
|
-
|
About this Antibody
|
Name
|
Recombinant Human BCMA/TNFRSF17 (Recombinant Human B-Cell Maturation Antigen; rHuBCMA);重组人B细胞成熟抗原/TNFRSF17
|
Synonyms
|
CD269; TNFRSF17; B cell maturation antigen; B-cell maturation protein; BCMAtumor necrosis factor receptor superfamily member 17; BCMB-cell maturation factor; CD269; CD269 antigen; tumor necrosis factor receptor superfamily, member 17
|
Purity
|
>98% by SDS-PAGE and HPLC analyses.
|
Biological Activity
|
Fully biologically active when compared to standard. The ED50 as determined by its ability to inhibit APRIL-mediated proliferation of anti-IgM stimulated murine B cells is no less than 40ng/ml, corresponding to a specific activity of >2.5×104IU/mg in the presence of 100ng/ml human APRIL.
|
Physical Appearance
|
Sterile Filtered White lyophilized (freeze-dried) powder.
|
Formulation
|
Lyophilized from a 0.2μM filtered concentrated solution in 30% acetonitrile, 0.1% TFA.
|
Endotoxin
|
Less than 1EU/μg of rHuBCMA as determined by LAL method.
|
Reconstitution
|
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0mg/ml. Stock solutions should be apportioned into working aliquots and stored at ≤-20℃. Further dilutions should be made in appropriate buffered solutions.
|
Category
|
Cytokine
|
Background
|
B-Cell Maturation Antigen (BCMA), encoded by the TNFRSF17 gene in humans. It is a member of the TNF receptor superfamily and a type III membrane protein containing one extracellular cysteine rich domain. It is expressed on mature B-cells and other B-cell lines. BCMA can binds to TNFSF13B/BLyS/BAFF and TNFSF13/APRIL, and has functions that promotes Bcell survival, plays a role in the regulation of humoral immunity, and activates NF-kappa-B and JNK BCMA.
|
Amino Acid Sequence
|
AGQCSQNEYF DSLLHACIPC QLRCSSNTPP LTCQRYCNAS VTNSVKGTNA
|
包装清单:
产品编号
|
产品名称
|
包装
|
P5376-5μg
|
Recombinant Human BCMA/TNFRSF17
|
5μg
|
P5376-20μg
|
Recombinant Human BCMA/TNFRSF17
|
20μg
|
P5376-100μg
|
Recombinant Human BCMA/TNFRSF17
|
100μg
|
P5376-1mg
|
Recombinant Human BCMA/TNFRSF17
|
1mg
|
-
|
说明书
|
1份
|
保存条件:
-20℃或更低温度保存,至少一年有效。由于蛋白的每次冻融均会引起部分失活,所以首次配制成相应浓度的储存液后(请根据产品简介中Reconstitution一栏的信息配制储存液),须分装后-20℃或更低温度冻存,以避免反复冻融。
注意事项:
由于有些塑料管壁对某些蛋白有较强的吸附作用,溶液中的蛋白很容易粘附在管壁上,并且粘附后的蛋白很难与管壁分离。而载体蛋白(Carrier protein,如0.1% BSA等)的主要作用是预先封闭塑料管壁上的蛋白结合位点,使细胞因子或重组蛋白不会粘附于管壁。所以一定要使用产品简介中Reconstitution一栏的信息配制储存液。
本产品仅限于专业人员的科学研究用,不得用于临床诊断或治疗,不得用于食品或药品,不得存放于普通住宅内。
为了您的安全和健康,请穿实验服并戴一次性手套操作。