产品编号 |
产品名称 |
产品包装 |
产品价格 |
P6645-2μg |
Recombinant Human MIP-4/CCL18 |
2μg |
464.00元 |
Species
|
Gene ID
|
Accession
|
Source
|
Length
|
MW
|
Tag
|
Human
|
6362
|
P55774
|
E. coli
|
69aa
|
7.9kDa
|
-
|
About this Antibody
|
Name
|
Recombinant Human MIP-4/CCL18 (Recombinant Human Macrophage Inflammatory Protein-4/CCL18; rHuMIP-4/CCL18);重组人巨噬细胞炎症蛋白4/CCL18
|
Synonyms
|
AMAC-1; DC-CK1; MIP-4; PARC; Alternative macrophage activation-associated CC chemokine 1; AMAC1CC chemokine ligand 18; AMAC-1Small-inducible cytokine A18; chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated); CKb7; DC-CK1CC chemokine PARC; DCCK1Macrophage inflammatory protein 4; Dendritic cell chemokine 1; MIP4; MIP-4C-C motif chemokine 18; PARCPulmonary and activation-regulated chemokine; SCYA18chemokine (C-C), dendritic; small inducible cytokine A18; small inducible cytokine subfamily A (Cys-Cys), member 18, pulmonary andactivation-regulated
|
Purity
|
>97% by SDS-PAGE and HPLC analyses.
|
Biological Activity
|
Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human T-lymphocytes is in a concentration of 1.0-10ng/ml.
|
Physical Appearance
|
Sterile Filtered White lyophilized (freeze-dried) powder.
|
Formulation
|
Lyophilized from a 0.2μm filtered concentrated solution in 20mM PB, pH7.4, 100mM NaCl.
|
Endotoxin
|
Less than 1EU/μg of rHuMIP-4/CCL18 as determined by LAL method.
|
Reconstitution
|
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0mg/ml. Stock solutions should be apportioned into working aliquots and stored at ≤-20℃. Further dilutions should be made in appropriate buffered solutions.
|
Category
|
Chemokines
|
Background
|
Human CCL18 is encoded by the CCL18 gene located on the chromosome 17. As also named MIP-4, it shares 61% sequence identity to human MIP-1α. CCL18 is mainly expressed by lung and some lymphoid tissues like lymph nodes express CCL18 at low level. It is chemotactic for both activated (CD3+) T cells and nonactivated (CD14-) lymphocytes, but not for monocytes or granulocytes. Involved in B-cell migration into B-cell follicles in lymph nodes. CCL18 plays a role in both humoral and cellmediated immunity responses.
|
Amino Acid Sequence
|
AQVGTNKELC CLVYTSWQIP QKFIVDYSET SPQCPKPGVI LLTKRGRQIC ADPNKKWVQK YISDLKLNA
|
包装清单:
产品编号
|
产品名称
|
包装
|
P6645-2μg
|
Recombinant Human MIP-4/CCL18
|
2μg
|
P6645-10μg
|
Recombinant Human MIP-4/CCL18
|
10μg
|
P6645-100μg
|
Recombinant Human MIP-4/CCL18
|
100μg
|
P6645-1mg
|
Recombinant Human MIP-4/CCL18
|
1mg
|
-
|
说明书
|
1份
|
保存条件:
-20℃或更低温度保存,至少一年有效。由于蛋白的每次冻融均会引起部分失活,所以首次配制成相应浓度的储存液后(请根据产品简介中Reconstitution一栏的信息配制储存液),须分装后-20℃或更低温度冻存,以避免反复冻融。
注意事项:
由于有些塑料管壁对某些蛋白有较强的吸附作用,溶液中的蛋白很容易粘附在管壁上,并且粘附后的蛋白很难与管壁分离。而载体蛋白(Carrier protein,如0.1% BSA等)的主要作用是预先封闭塑料管壁上的蛋白结合位点,使细胞因子或重组蛋白不会粘附于管壁。所以一定要使用产品简介中Reconstitution一栏的信息配制储存液。
本产品仅限于专业人员的科学研究用,不得用于临床诊断或治疗,不得用于食品或药品,不得存放于普通住宅内。
为了您的安全和健康,请穿实验服并戴一次性手套操作。