产品编号 |
产品名称 |
产品包装 |
产品价格 |
P5439-1mg |
Recombinant Human sTNF RI/TNFRSF1A |
1mg |
15444.00元 |
Species
|
Gene ID
|
Accession
|
Source
|
Length
|
MW
|
Tag
|
Human
|
7132
|
P19438
|
E. coli
|
190aa
|
21.2kDa
|
-
|
About this Antibody
|
Name
|
Recombinant Human sTNF RI/TNFRSF1A (Recombinant Human soluble Tumor Necrosis Factor Receptor Type I/TNFRSF1A; rHusTNF RI/TNFRSF1A);重组人可溶性肿瘤坏死因子受体I型/TNFRSF1A
|
Synonyms
|
CD120a; TNFRSF1A; CD120a; CD120a antigen; FPF; p55; p55-R; p60; TNFARMGC19588; TNF-R; TNF-R1; TNFR1TBP1; TNFR55; TNF-R55; TNFR60; TNF-RI; TNF-R-I; TNFR-I; tumor necrosis factor binding protein 1; Tumor necrosis factor receptor 1; tumor necrosis factor receptor 1A isoform beta; tumor necrosis factor receptor superfamily member 1A; tumor necrosis factor receptor superfamily, member 1A; tumor necrosis factor receptor type 1; Tumor necrosis factor receptor type I; tumor necrosis factor-alpha receptor
|
Purity
|
>97% by SDS-PAGE and HPLC analyses.
|
Biological Activity
|
Fully biologically active when compared to standard. The ED50 as determined by its ability to inhibit the TNF-alpha mediated cytotoxicity in the L-929 cells is less than 0.05μg/ml, corresponding to a specific activity of >2×104IU/mg in the presence of 0.25ng/ml of rHuTNF-alpha.
|
Physical Appearance
|
Sterile Filtered White lyophilized (freeze-dried) powder.
|
Formulation
|
Lyophilized from a 0.2μm filtered solution in PBS, pH7.4.
|
Endotoxin
|
Less than 0.1EU/μg of rHusTNF RI/TNFRSF1A as determined by LAL method.
|
Reconstitution
|
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0mg/ml. Stock solutions should be apportioned into working aliquots and stored at ≤-20℃. Further dilutions should be made in appropriate buffered solutions.
|
Category
|
Cytokine
|
Background
|
TNF RI, also named as TNFR-I, TNF R1, TNFRSF1A, p55 and p60, belongs to the tumor necrosis factor receptor superfamily, and it is encoded by the TNFRSF1A gene in human. TNF RI is a universally expressed protein and is thought to form homotrimers after ligand binding. TNF RI is one of the major receptors for the TNF-α. This receptor can activate the transcription factor NF-κB, mediate apoptosis, and function as a regulator of inflammation. Mature human soluble TNF RI shares 68%~73% amino acid sequence identity with murine, rat, bovine and porcine soluble TNF RI.
|
Amino Acid Sequence
|
IYPSGVIGLV PHLGDREKRD SVCPQGKYIH PQNNSICCTK CHKGTYLYND CPGPGQDTDC RECESGSFTA SENHLRHCLS CSKCRKEMGQ VEISSCTVDR DTVCGCRKNQ YRHYWSENLF QCFNCSLCLN GTVHLSCQEK QNTVCTCHAG FFLRENECVS CSNCKKSLEC TKLCLPQIEN VKGTEDSGTT
|
包装清单:
产品编号
|
产品名称
|
包装
|
P5439-5μg
|
Recombinant Human sTNF RI/TNFRSF1A
|
5μg
|
P5439-20μg
|
Recombinant Human sTNF RI/TNFRSF1A
|
20μg
|
P5439-100μg
|
Recombinant Human sTNF RI/TNFRSF1A
|
100μg
|
P5439-1mg
|
Recombinant Human sTNF RI/TNFRSF1A
|
1mg
|
-
|
说明书
|
1份
|
保存条件:
-20℃或更低温度保存,至少一年有效。由于蛋白的每次冻融均会引起部分失活,所以首次配制成相应浓度的储存液后(请根据产品简介中Reconstitution一栏的信息配制储存液),须分装后-20℃或更低温度冻存,以避免反复冻融。
注意事项:
由于有些塑料管壁对某些蛋白有较强的吸附作用,溶液中的蛋白很容易粘附在管壁上,并且粘附后的蛋白很难与管壁分离。而载体蛋白(Carrier protein,如0.1% BSA等)的主要作用是预先封闭塑料管壁上的蛋白结合位点,使细胞因子或重组蛋白不会粘附于管壁。所以一定要使用产品简介中Reconstitution一栏的信息配制储存液。
本产品仅限于专业人员的科学研究用,不得用于临床诊断或治疗,不得用于食品或药品,不得存放于普通住宅内。
为了您的安全和健康,请穿实验服并戴一次性手套操作。