Recombinant Murine DHH C23II

Species

Gene ID

Accession

Source

Length

MW

Tag

Mouse

13363

Q61488

E. coli

177aa

20kDa

－

About this Antibody

Name

Recombinant Murine DHH C23II (Recombinant Murine Desert Hedgehog Cys23IleIle; rMuDHH C23II)； Recombinant Mouse DHH C23II ; 重组小鼠沙漠刺猬因子C23II

Synonyms

DHH; desert hedgehog; desert hedgehog (Drosophila) homolog; desert hedgehog homolog; desert hedgehog protein; HHG-3MGC35145

Purity

>98% by SDS-PAGE and HPLC analyses.

Biological Activity

Fully biologically active when compared to standard. The ED50 as determined by its ability to induce alkaline phosphatase production by murine MC3T3-E1 cells is 5-20μg/ml.

Physical Appearance

Sterile Filtered White lyophilized (freeze-dried) powder.

Formulation

Lyophilized from a 0.2μm filtered concentrated solution in PBS, pH7.4, 1mM DTT, 0.05% Tween-80.

Endotoxin

Less than 0.1EU/μg of rMuDHH C23II as determined by LAL method.

Reconstitution

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0mg/ml. Stock solutions should be apportioned into working aliquots and stored at ≤-20℃. Further dilutions should be made in appropriate buffered solutions.

Category

Others

Background

Desert hedgehog protein also known as HHG-3 is a member of the hedgehog family which is encoded by the DHH gene. It is expressed in adult testes but not expressed in limb buds. DHH may be as a precursor that is auto-catalytically cleaved; the N-terminal portion is soluble and contains the signalling activity while the C-terminal portion is involved in precursor processing. Besides, DHH may have a function as a spermatocyte survival factor in the testes. Within the N-terminal peptide, murine DHH shares 97% and 100% amino acid (a.a.) sequence identity with human and rat DHH, respectively.

Amino Acid Sequence

IIGPGRGPVG RRRYVRKQLV PLLYKQFVPS MPERTLGASG PAEGRVTRGS ERFRDLVPNY NPDIIFKDEE NSGADRLMTE RCKERVNALA IAVMNMWPGV RLRVTEGWDE DGHHAQDSLH YEGRALDITT SDRDRNKYGL LARLAVEAGF DWVYYESRNH IHVSVKADNS LAVRAGG

产品编号

产品名称

包装

P7338-5μg

Recombinant Murine DHH C23II

5μg

P7338-25μg

Recombinant Murine DHH C23II

25μg

P7338-100μg

Recombinant Murine DHH C23II

100μg

P7338-1mg

Recombinant Murine DHH C23II

1mg

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说明书

1份