Recombinant Murine Exodus-2/CCL21

Species

Gene ID

Accession

Source

Length

MW

Tag

Mouse

18829

P84444

E. coli

110aa

12.1kDa

－

About this Antibody

Name

Recombinant Murine Exodus-2/CCL21 (Recombinant Murine Exodus-2/CCL21; rMuExodus-2/CCL21)；Recombinant Mouse Exodus-2/CCL21 ; 重组小鼠嗜酸粒细胞趋化因子2/CCL21

Synonyms

6Ckine; exodus-2; SCYA21; SLC; TCA-4; 6CkineSmall-inducible cytokine A21; Beta-chemokine exodus-2; chemokine (C-C motif) ligand 21; CKb9; member 21; SCYA21MGC34555; secondary lymphoid tissue chemokine; SLCSecondary lymphoid-tissue chemokine

Purity

>97% by SDS-PAGE and HPLC analyses.

Biological Activity

Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using murine T-lymphocytes is in a concentration range of 10-100ng/ml.

Physical Appearance

Sterile Filtered White lyophilized (freeze-dried) powder.

Formulation

Lyophilized from a 0.2μm filtered concentrated solution in 20mM PB, pH7.4, 150mM NaCl.

Endotoxin

Less than 1EU/μg of rMuExodus-2/CCL21 as determined by LAL method.

Reconstitution

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0mg/ml. Stock solutions should be apportioned into working aliquots and stored at ≤-20℃. Further dilutions should be made in appropriate buffered solutions.

Category

Chemokines

Background

CCL21 is encoded by CCL21 gene that is located in Chr. 4 and shows 21-33% identity to other CC chemokines. This chemokine contains the four conserved cysteines characteristic of β chemokines plus two additional cysteines in its unusually long carboxylterminal domain. Human and mouse CCL21 are highly conserved, exhibiting 86% amino acid sequence identity. CCL21 is highly expressed in lymph nodes of certain endothelial cells, and in the spleen and appendix. It elicits effects by binding with CCR7, having functions of T and B lymphocytes chemotaxis and inhibiting hematopoiesis.

Amino Acid Sequence

SDGGGQDCCL KYSQKKIPYS IVRGYRKQEP SLGCPIPAIL FLPRKHSKPE LCANPEEGWV QNLMRRLDQP PAPGKQSPGC RKNRGTSKSG KKGKGSKGCK RTEQTQPSRG

产品编号

产品名称

包装

P6825-5μg

Recombinant Murine Exodus-2/CCL21

5μg

P6825-20μg

Recombinant Murine Exodus-2/CCL21

20μg

P6825-100μg

Recombinant Murine Exodus-2/CCL21

100μg

P6825-1mg

Recombinant Murine Exodus-2/CCL21

1mg

-

说明书

1份