Recombinant Murine FGF-18

Species

Gene ID

Accession

Source

Length

MW

Tag

Mouse

14172

O89101

E. coli

180aa

21kDa

－

About this Antibody

Name

Recombinant Murine FGF-18 (Recombinant Murine Fibroblast Growth Factor-18; rMuFGF-18)；Recombinant Mouse FGF-18 ; 重组小鼠成纤维细胞生长因子18

Synonyms

Fibroblast growth factor 18; FGF-18; zFGF5; Fgf18

Purity

>95% by SDS-PAGE and HPLC analyses.

Biological Activity

Fully biologically active when compared to standard. The ED50 as determined by thymidine uptake assay using FGF-receptors transfected BaF3 cells is less than 0.5ng/ml, corresponding to a specific activity of >2.0×10⁶IU/mg.

Physical Appearance

Sterile Filtered White lyophilized (freeze-dried) powder.

Formulation

Lyophilized from a 0.2μm filtered concentrated solution in PBS, pH7.4, 500mM NaCl.

Endotoxin

Less than 1EU/μg of rMuFGF-18 as determined by LAL method.

Reconstitution

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0mg/ml. Stock solutions should be apportioned into working aliquots and stored at ≤-20℃. Further dilutions should be made in appropriate buffered solutions.

Category

Cytokine

Background

Murine FGF-18 is encoded by the FGF18 gene. By phylogenetic analysis and gene location analysis, FGF-18 is divided into FGF-8 subfamily which has three members FGF-8, FGF-17 and FGF-18. Using FGF knockout mice model, the numbers of this subfamily were testified that have crucial roles of in embryo development. FGF-18–/– mice have decreased expression of osteogenic markers and delayed long-bone ossification. FGF-18 has been shown in vitro that this protein is able to induce neurite outgrowth in PC12 cells. In addition, it also has significant roles in lung development and has an anabolic effect on cartilage formation.

Amino Acid Sequence

EENVDFRIHV ENQTRARDDV SRKQLRLYQL YSRTSGKHIQ VLGRRISARG EDGDKYAQLL VETDTFGSQV RIKGKETEFY LCMNRKGKLV GKPDGTSKEC VFIEKVLENN YTALMSAKYS GWYVGFTKKG RPRKGPKTRE NQQDVHFMKR YPKGQAELQK PFKYTTVTKR SRRIRPTHPG

产品编号

产品名称

包装

P6096-5μg

Recombinant Murine FGF-18

5μg

P6096-25μg

Recombinant Murine FGF-18

25μg

P6096-100μg

Recombinant Murine FGF-18

100μg

P6096-1mg

Recombinant Murine FGF-18

1mg

-

说明书

1份