Recombinant Murine KGF-1/FGF-7

Species

Gene ID

Accession

Source

Length

MW

Tag

Mouse

14178

P36363

E. coli

163aa

18.7kDa

－

About this Antibody

Name

Recombinant Murine KGF-1/FGF-7 (Recombinant Murine Keratinocyte Growth Factor-1/FGF-7; rMuKGF-1/FGF-7)；Recombinant Mouse KGF-1/FGF-7 ; 重组小鼠角质细胞生长因子1/成纤维细胞生长因子7

Synonyms

FGF7; FGF-7; FGF-7; fibroblast growth factor 7HBGF-7; Heparin-binding growth factor 7; keratinocyte growth factor; KGFfibroblast growth factor 7 (keratinocyte growth factor)

Purity

>96% by SDS-PAGE and HPLC analyses.

Biological Activity

Fully biologically active when compared to standard. The ED50 as determined by thymidine uptake assay using FGF-receptors transfected BaF3 cells is less than 10ng/ml, corresponding to a specific activity of >1.0×10⁵IU/mg.

Physical Appearance

Sterile Filtered White lyophilized (freeze-dried) powder.

Formulation

Lyophilized from a 0.2μm filtered solution in 20mM PB, pH8.0, 1M NaCl.

Endotoxin

Less than 1EU/μg of rMuKGF-1/FGF-7 as determined by LAL method.

Reconstitution

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0mg/ml. Stock solutions should be apportioned into working aliquots and stored at ≤-20℃. Further dilutions should be made in appropriate buffered solutions.

Category

Cytokine

Background

Murine KGF-1 also known as Fibroblast growth factor 7 (FGF-7), is encoded by the FGF7 gene. KGF-1 only binds to the b splice form of the tyrosine kinase receptor, FGFR2b/KGFR. Affinity between KGF-1 and its receptor can be increased by heparin or heparin sulfate proteoglycan. FGF-10, also called keratinocyte growth factor 2 (KGF-2), shares 51% amino acid sequence identity and similar function to KGF-1, but uses an additional receptor, FGFR2c. KGF-1 plays an important role in the regulation of embryonic development, cell proliferation and cell differentiation. KGF-1 actives on keratinocytes, and exhibits mitogenic activity for epidermal cells, but essentially no activity for fibroblasts. KGF-1 has species crossactive, murine KGF-1 shares 96% amino acid sequence identity with human and rat.

Amino Acid Sequence

CNDMSPEQTA TSVNCSSPER HTRSYDYMEG GDIRVRRLFC RTQWYLRIDK RGKVKGTQEM KNSYNIMEIR TVAVGIVAIK GVESEYYLAM NKEGKLYAKK ECNEDCNFKE LILENHYNTY ASAKWTHSGG EMFVALNQKG IPVKGKKTKK EQKTAHFLPM AIT

产品编号

产品名称

包装

P6078-2μg

Recombinant Murine KGF-1/FGF-7

2μg

P6078-10μg

Recombinant Murine KGF-1/FGF-7

10μg

P6078-100μg

Recombinant Murine KGF-1/FGF-7

100μg

P6078-1mg

Recombinant Murine KGF-1/FGF-7

1mg

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说明书

1份