Recombinant Murine MCP-2/CCL8

Species

Gene ID

Accession

Source

Length

MW

Tag

Mouse

20307

Q9Z121

E. coli

74aa

8.5kDa

－

About this Antibody

Name

Recombinant Murine MCP-2/CCL8 (Recombinant Murine Monocyte Chemotactic Protein-2/CCL8; rMuMCP-2/CCL8)；Recombinant Mouse MCP-2/CCL8 ; 重组小鼠单核细胞趋化蛋白2/CCL8

Synonyms

MCP-2; C-C motif chemokine 8; chemokine (C-C motif) ligand 8; HC14; MCP2; MCP-2; member 8 (monocyte chemotactic protein 2); monocyte chemoattractant protein 2; SCYA10; small-inducible cytokine A8

Purity

>97% by SDS-PAGE and HPLC analyses.

Biological Activity

Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human peripheral blood monocytes is in a concentration range of 10-100ng/ml.

Physical Appearance

Sterile Filtered White lyophilized (freeze-dried) powder.

Formulation

Lyophilized from a 0.2μm filtered concentrated solution in 20mM PB, pH7.4, 150mM NaCl.

Endotoxin

Less than 1EU/μg of rMuMCP-2/CCL8 as determined by LAL method.

Reconstitution

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0mg/ml. Stock solutions should be apportioned into working aliquots and stored at ≤-20℃. Further dilutions should be made in appropriate buffered solutions.

Category

Chemokines

Background

Murine CCL8, also known as monocyte chemotactic protein 2 (MCP-2), is belonging to the CC chemokine family and is encoded by the gene CCL8 in mouse. MCP-2 has two homogeneous MCP-1 (CCL2) and MCP-3 (CCL7). These three MCPs were found by IL-1-beta triggered human MG-63 osteosarcoma cells. CCL8 shares 62% amino acid sequence identity with MCP-1, and shares 58% amino acid sequence identity with MCP-2. CCL8 has chemotactic fuction for monocytes, eosinophils and neutrophils. In addition, it can also chemoattract activated NK cells.

Amino Acid Sequence

GPDKAPVTCC FHVLKLKIPL RVLKSYERIN NIQCPMEAVV FQTKQGMSLC VDPTQKWVSE YMEILDQKSQ ILQP

产品编号

产品名称

包装

P6794-5μg

Recombinant Murine MCP-2/CCL8

5μg

P6794-20μg

Recombinant Murine MCP-2/CCL8

20μg

P6794-100μg

Recombinant Murine MCP-2/CCL8

100μg

P6794-1mg

Recombinant Murine MCP-2/CCL8

1mg

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说明书

1份