Recombinant Murine MIP-1α/CCL3

Species

Gene ID

Accession

Source

Length

MW

Tag

Mouse

20302

P10855

E. coli

69aa

7.9kDa

－

About this Antibody

Name

Recombinant Murine MIP-1α/CCL3 (Recombinant Murine Macrophage Inflammatory Protein-1α/CCL3; rMuMIP-1α/CCL3)；Recombinant Mouse MIP-1α/CCL3 ; 重组小鼠巨噬细胞炎症蛋白1α/CCL3

Synonyms

LD78a; MIP-1 alpha; C-C motif chemokine 3; MIP1-(a); AI323804; chemokine (C-C motif) ligand 3; G0S19-1; LD78alpha; Mip1a; MIP-1alpha; MIP1-alpha; Scya3

Purity

>98% by SDS-PAGE and HPLC analyses.

Biological Activity

Fully biologically active when compared to standard. The biological activity determined by a chemoattract bioassay using murine splenocytes is in a concentration range of 10-100ng/ml.

Physical Appearance

Sterile Filtered White lyophilized (freeze-dried) powder.

Formulation

Lyophilized from a 0.2μm filtered concentrated solution in 30% Acetonitrile and 0.1% TFA.

Endotoxin

Less than 0.1EU/μg of rMuMIP-1α/CCL3 as determined by LAL method.

Reconstitution

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0mg/ml. Stock solutions should be apportioned into working aliquots and stored at ≤-20℃. Further dilutions should be made in appropriate buffered solutions.

Category

Chemokines

Background

CCL3, also known as macrophage inflammatory protein-1α (MIP-1α), is a cytokine belonging to the CC chemokine family that is involved in the acute inflammatory state in the recruitment and activation of polymorphonuclear leukocytes. Studies showed CCL3 can bind to CCR1, CCR4 and CCR5. MIP-1α can induce a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). Recombinant murine MIP-1α is a 7.9kDa protein containing 69 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines and mature mouse CCL3 shares 73%, 91% and 82% amino acid sequence identity with human, rat and cotton rat CCL3, respectively.

Amino Acid Sequence

APYGADTPTA CCFSYSRKIP RQFIVDYFET SSLCSQPGVI FLTKRNRQIC ADSKETWVQE YITDLELNA

产品编号

产品名称

包装

P6771-2μg

Recombinant Murine MIP-1α/CCL3

2μg

P6771-10μg

Recombinant Murine MIP-1α/CCL3

10μg

P6771-100μg

Recombinant Murine MIP-1α/CCL3

100μg

P6771-1mg

Recombinant Murine MIP-1α/CCL3

1mg

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说明书

1份