Recombinant Murine MIP-2/CXCL2

Species

Gene ID

Accession

Source

Length

MW

Tag

Mouse

20310

P10889

E. coli

73aa

7.8kDa

－

About this Antibody

Name

Recombinant Murine MIP-2/CXCL2 (Recombinant Murine Macrophage Inflammatory Protein-2/CXCL2; rMuMIP-2/CXCL2)；Recombinant Mouse MIP-2/CXCL2 ; 重组小鼠巨噬细胞炎症蛋白2/CXCL2

Synonyms

CINC-3; GRO beta; MGSA-beta; MIP-2; chemokine (C-X-C motif) ligand 2; CINC-2a; C-X-C Motif Chemokine 2; GRO2; GRO2 oncogene; GROb; GROB; gro-beta; Gro-beta; Growth-regulated protein beta; Macrophage inflammatory protein 2-alpha; melanoma growth stimulatory activity beta; MGSA beta; MGSA-b; MIP2; MIP2A; MIP-2a; MIP2-alpha; SCYB2

Purity

>97% by SDS-PAGE and HPLC analyses.

Biological Activity

Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human neutrophils is in a concentration range of 1.0-10ng/ml.

Physical Appearance

Sterile Filtered White lyophilized (freeze-dried) powder.

Formulation

Lyophilized from a 0.2μm filtered concentrated solution in 20mM PB, pH7.4, 150mM NaCl.

Endotoxin

Less than 1EU/μg of rMuMIP-2/CXCL2 as determined by LAL method.

Reconstitution

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0mg/ml. Stock solutions should be apportioned into working aliquots and stored at ≤-20℃. Further dilutions should be made in appropriate buffered solutions.

Category

Chemokines

Background

Murine CXCL2, also named MIP-2, is belonging to the CXC chemokine family. It is encoded by the gene CXCL2. CXCL2 shares 90% amino acid sequence with CXCL1/GROα. It is member of the intercrine alpha (chemokine C-X-C) subfamily of chemokines. This chemokine is secreted from a murine macrophage cell line. The functional receptor for CXCL2 has been identified as CXCR2. CXCL2 is chemotactic for polymorphonuclear leukocytes and hematopoietic stem cells. Similar to other GRO proteins, CXCL2 is potent neutrophil attractants and activators. In addition, it is also active toward basophils. The amino acid sequence of murine CXCL2 is 60% identical to human CXCL2.

Amino Acid Sequence

AVVASELRCQ CLKTLPRVDF KNIQSLSVTP PGPHCAQTEV IATLKGGQKVCLDPEAPLVQ KIIQKILNKG KAN

产品编号

产品名称

包装

P6713-5μg

Recombinant Murine MIP-2/CXCL2

5μg

P6713-20μg

Recombinant Murine MIP-2/CXCL2

20μg

P6713-100μg

Recombinant Murine MIP-2/CXCL2

100μg

P6713-1mg

Recombinant Murine MIP-2/CXCL2

1mg

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说明书

1份