Recombinant Murine MIP-3α/CCL20

Species

Gene ID

Accession

Source

Length

MW

Tag

Mouse

20297

O89093

E. coli

70aa

8kDa

－

About this Antibody

Name

Recombinant Murine MIP-3α/CCL20 (Recombinant Murine Macrophage Inflammatory Protein-3α/CCL20; rMuMIP-3α/CCL20)；Recombinant Mouse MIP-3α/CCL20 ; 重组小鼠巨噬细胞炎症蛋白3α/CCL20

Synonyms

exodus-1; LARC; MIP-3 alpha; beta chemokine exodus-1; Beta-chemokine exodus-1; CC chemokine LARC; C-C motif chemokine 20; chemokine (C-C motif) ligand 20; CKb4; exodus-1; LARCLiver and activation-regulated chemokine; MIP-3a; MIP-3-alpha; MIP3AMacrophage inflammatory protein 3 alpha; SCYA20Small-inducible cytokine A20; small inducible cytokine subfamily A (Cys-Cys), member 20; ST38

Purity

>96% by SDS-PAGE and HPLC analyses.

Biological Activity

Fully biologically active when compared to standard. The biologically active determined by a chemotaxis bioassay using human CCR6 transfected murine BaF3 cells is in a concentration range of 0.1-10ng/ml.

Physical Appearance

Sterile Filtered White lyophilized (freeze-dried) powder.

Formulation

Lyophilized from a 0.2μm filtered concentrated solution in PBS, pH7.4.

Endotoxin

Less than 1EU/μg of rMuMIP-3α/CCL20 as determined by LAL method.

Reconstitution

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0mg/ml. Stock solutions should be apportioned into working aliquots and stored at ≤-20℃. Further dilutions should be made in appropriate buffered solutions.

Category

Chemokines

Background

CCL20, also named LARC (Liver and Activation-regulated Chemokine), is encoded by CCL20 located on chromosome 1 in mouse. The expression can be induced by LPS and some inflammatory cytokines, and it is at a high level in lymph nodes, PBL, fatal liver, fatal lung, appendix and so on. CCL20 has functions of chemotactic towards lymphocytes and dendritic cells. Additionally, it promotes the adhesion of memory CD4⁺ T cells and inhibits colony formation of bone marrow myeloid immature progenitors. CCL20 elicits it effects by binding with CCR6 receptor.

Amino Acid Sequence

ASNYDCCLSY IQTPLPSRAI VGFTRQMADE ACDINAIIFH TKKRKSVCAD PKQNWVKRAV NLLSLRVKKM

产品编号

产品名称

包装

P6821-5μg

Recombinant Murine MIP-3α/CCL20

5μg

P6821-20μg

Recombinant Murine MIP-3α/CCL20

20μg

P6821-100μg

Recombinant Murine MIP-3α/CCL20

100μg

P6821-1mg

Recombinant Murine MIP-3α/CCL20

1mg

-

说明书

1份