Recombinant Murine PF-4/CXCL4

Species

Gene ID

Accession

Source

Length

MW

Tag

Mouse

56744

Q9Z126

E. coli

76aa

8.2kDa

－

About this Antibody

Name

Recombinant Murine PF-4/CXCL4 (Recombinant Murine Platelet Factor-4/CXCL4; rMuPF-4/CXCL4)；Recombinant Mouse PF-4/CXCL4 ; 重组小鼠血小板因子4/CXCL4

Synonyms

PF4; chemokine (C-X-C motif) ligand 4; C-X-C motif chemokine 4; CXCL4iroplact; Iroplact; MGC138298; Oncostatin-A; PF-4; platelet factor 4; SCYB4oncostatin-A

Purity

>97% by SDS-PAGE and HPLC analyses.

Biological Activity

Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human neutrophils is in a concentration of 10-100ng/ml.

Physical Appearance

Sterile Filtered White lyophilized (freeze-dried) powder.

Formulation

Lyophilized from a 0.2μm filtered concentrated solution in 20mM PB, 1.5 M NaCl, pH7.4.

Endotoxin

Less than 1EU/μg of rMuPF-4/CXCL4 as determined by LAL method.

Reconstitution

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0mg/ml. Stock solutions should be apportioned into working aliquots and stored at ≤-20℃. Further dilutions should be made in appropriate buffered solutions.

Category

Chemokines

Background

CXCL4 (PF4) is a small cytokine belonging to the CXC chemokine family and it is also known as chemokine (C-X-C motif) ligand 4 (CXCL4). This chemokine is released from alpha-granules of activated platelets during platelet aggregation and neutralizes the anticoagulant effect of heparin because it binds more strongly to heparin than to the chondroitin-4-sulfate chains of the carrier molecule. CXCL4 interacts with a splice variant of the chemokine receptor CXCR3. Recombinant mouse CXCL4 contains 76 amino acids which is a single non-glycosylated polypeptide chain. Specifically, Human and mouse CXCL4 share about a 60% identity.

Amino Acid Sequence

VTSAGPEESD GDLSCVCVKT ISSGIHLKHI TSLEVIKAGR HCAVPQLIAT LKNGRKICLD RQAPLYKKVI KKILES

产品编号

产品名称

包装

P6722-5μg

Recombinant Murine PF-4/CXCL4

5μg

P6722-20μg

Recombinant Murine PF-4/CXCL4

20μg

P6722-100μg

Recombinant Murine PF-4/CXCL4

100μg

P6722-1mg

Recombinant Murine PF-4/CXCL4

1mg

-

说明书

1份