Recombinant Murine TRAIL/TNFSF10

Species

Gene ID

Accession

Source

Length

MW

Tag

Mouse

22035

P50592

E. coli

175aa

20.2kDa

－

About this Antibody

Name

Recombinant Murine TRAIL/TNFSF10 (Recombinant Murine TNF-related apoptosisinducing Ligand/TNFSF10; rMuTRAIL/TNFSF10)；Recombinant Mouse TRAIL/TNFSF10 ; 重组小鼠诱导肿瘤坏死因子凋亡相关配体/TNFSF10

Synonyms

CD253; TNFSF10; Apo-2 ligand; APO2L; Apo-2Ltumor necrosis factor (ligand) family, member 10; APO2Ltumor necrosis factor apoptosis-inducing ligand splice variant delta; CD253; CD253 antigen; Protein TRAIL; TL2; TNF-related apoptosis-inducing ligand; TRAILTNF-related apoptosis inducing ligand TRAIL; tumor necrosis factor (ligand) superfamily, member 10; tumor necrosis factor ligand superfamily member 10

Purity

>95% by SDS-PAGE and HPLC analyses.

Biological Activity

Fully biologically active when compared to standard. The ED50 as determined by a cytotoxicity assay using murine L929 cells is less than 0.5ng/ml, corresponding to a specific activity of >2.0×10⁶IU/mg in the presence of actinomycin D.

Physical Appearance

Sterile Filtered White lyophilized (freeze-dried) powder.

Formulation

Lyophilized from a 0.2μm filtered concentrated solution in PBS, pH7.4, with 3mM DTT.

Endotoxin

Less than 0.1EU/μg of rMuTRAIL/TNFSF10 as determined by LAL method.

Reconstitution

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0mg/ml. Stock solutions should be apportioned into working aliquots and stored at ≤-20℃. Further dilutions should be made in appropriate buffered solutions.

Category

Cytokine

Background

TNF-related apoptosis-inducing ligand (TRAIL), also known as Apo-2 ligand and TNFSF10, is a type II transmembrane protein with a carboxy-terminal extracellular domain that exhibits homology to other TNF superfamily members. Among TNF superfamily members, TRAIL is the most homologous to Fas Ligand, sharing 28% amino acid sequence identity in their extracellular domains. Murine TRAIL shares 65% amino acid sequence identity with human TRAIL.

Amino Acid Sequence

MPRGGRPQKV AAHITGITRR SNSALIPISK DGKTLGQKIE SWESSRKGHS FLNHVLFRNG ELVIEQEGLY YIYSQTYFRF QEAEDASKMV SKDKVRTKQL VQYIYKYTSY PDPIVLMKSA RNSCWSRDAE YGLYSIYQGG LFELKKNDRI FVSVTNEHLM DLDQEASFFG AFLIN

产品编号

产品名称

包装

P6042-10μg

Recombinant Murine TRAIL/TNFSF10

10μg

P6042-50μg

Recombinant Murine TRAIL/TNFSF10

50μg

P6042-100μg

Recombinant Murine TRAIL/TNFSF10

100μg

P6042-1mg

Recombinant Murine TRAIL/TNFSF10

1mg

-

说明书

1份