Recombinant Rat CINC-3/CXCL2

Species

Gene ID

Accession

Source

Length

MW

Tag

Rat

114105

P30348

E. coli

73aa

7.9kDa

－

About this Antibody

Name

Recombinant Rat CINC-3/CXCL2 (Recombinant Rat Cytokine-induced Neutrophil Chemoattractant 3/CXCL2; rRtCINC-3/CXCL2)；重组大鼠中性粒细胞趋化因子3/CXCL2

Synonyms

CINC-3; GRO beta; MGSA-beta; MIP-2; chemokine (C-X-C motif) ligand 2; CINC-2a; C-X-C Motif Chemokine 2; GRO2; GRO2 oncogene; GROb; GROB; gro-beta; Gro-beta; Growth-regulated protein beta; Macrophage inflammatory protein 2-alpha; melanoma growth stimulatory activity beta; MGSA beta; MGSA-b; MIP2; MIP2A; MIP-2a; MIP2-alpha; SCYB2

Purity

>98% by SDS-PAGE and HPLC analyses.

Biological Activity

Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using rat neutrophils is in a concentration range of 10-100ng/ml.

Physical Appearance

Sterile Filtered White lyophilized (freeze-dried) powder.

Formulation

Lyophilized from a 0.2μm filtered concentrated solution in PBS, pH7.4.

Endotoxin

Less than 1EU/μg of rRtCINC-3/CXCL2 as determined by LAL method.

Reconstitution

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0mg/ml. Stock solutions should be apportioned into working aliquots and stored at ≤-20℃. Further dilutions should be made in appropriate buffered solutions.

Category

Chemokines

Background

Rat CXCL2 also named CINC-3, belongs to the CXC chemokine family. It is encoded by the gene CXCL2 and shares 90% amino acid sequence with CXCL1/GROα. It is member of the intercrine alpha (chemokine C-X-C) subfamily of chemokines. This chemokine is expressed by cytokine-stimulated rat alveolar macrophages and fibroblasts. The functional receptor for CXCL2 has been identified as CXCR2. CXCL2 is chemotactic for polymorphonuclear leukocytes and hematopoietic stem cells. Similar to other GRO proteins, CXCL2 is potent neutrophil attractants and activators. In addition, it is also active toward basophils. The amino acid sequence of rat CXCL2 is 88% identical to murine CXCL2.

Amino Acid Sequence

VVVASELRCQ CLTTLPRVDF KNIQSLTVTP PGPHCAQTEV IATLKDGHEV CLNPEAPLVQ RIVQKILNKG KAN

产品编号

产品名称

包装

P6857-5μg

Recombinant Rat CINC-3/CXCL2

5μg

P6857-25μg

Recombinant Rat CINC-3/CXCL2

25μg

P6857-100μg

Recombinant Rat CINC-3/CXCL2

100μg

P6857-1mg

Recombinant Rat CINC-3/CXCL2

1mg

-

说明书

1份