Recombinant Rat Eotaxin/CCL11

Species

Gene ID

Accession

Source

Length

MW

Tag

Rat

29397

P97545

E. coli

74aa

8.4kDa

－

About this Antibody

Name

Recombinant Rat Eotaxin/CCL11 (Recombinant Rat Eotaxin/CCL11; rRtEotaxin/CCL11)；重组大鼠嗜酸性粒细胞趋化因子/CCL11

Synonyms

Eotaxin; C-C motif chemokine 11; chemokine (C-C motif) ligand 11; Eosinophil chemotactic protein; eotaxin; eotaxin-1; MGC22554; SCYA11Small-inducible cytokine A11; small inducible cytokine subfamily A (Cys-Cys), member 11 (eotaxin)

Purity

>96% by SDS-PAGE and HPLC analyses.

Biological Activity

Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using purified eosinophils is in a concentration range of 0.1-1.0μg/ml.

Physical Appearance

Sterile Filtered White lyophilized (freeze-dried) powder.

Formulation

Lyophilized from a 0.2μm filtered concentrated solution in 20mM PB, pH7.4, 150mM NaCl.

Endotoxin

Less than 1EU/μg of rRtEotaxin/CCL11 as determined by LAL method.

Reconstitution

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0mg/ml. Stock solutions should be apportioned into working aliquots and stored at ≤-20℃. Further dilutions should be made in appropriate buffered solutions.

Category

Chemokines

Background

CCL11 encoded by the gene CCL11is belonging to the CC chemokine family. It is a potent eosinophil chemoattractant that was originally purified from bronchoalveolar lavage fluid of guinea pigs sensitized by aerosol challenge with ovalbumin. CCL11 is a strong and specific eosinophil chemoattractant in vitro. It can directly chemotactic for eosinophils, but not for monocytes or neutrophils. CCR3 has been identified to be a specific CCL11 receptor. CCR3 has also been shown to serve as a cofactor for a restricted subset of primary HIV viruses and binding of CCL11 to CCR3 inhibited infection by the HIV isolates.

Amino Acid Sequence

HPGSIPTSCC FTMTSKKIPN TLLKSYKRIT NNRCTLKAIV FKTKLGKEIC ADPKKKWVQD ATKHLDQKLQ TPKP

产品编号

产品名称

包装

P6924-5μg

Recombinant Rat Eotaxin/CCL11

5μg

P6924-20μg

Recombinant Rat Eotaxin/CCL11

20μg

P6924-100μg

Recombinant Rat Eotaxin/CCL11

100μg

P6924-1mg

Recombinant Rat Eotaxin/CCL11

1mg

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说明书

1份