Recombinant Rat GDNF

Species

Gene ID

Accession

Source

Length

MW

Tag

Rat

25453

Q07731

E. coli

134aa

29.8kDa

－

About this Antibody

Name

Recombinant Rat GDNF (Recombinant Rat Glial Cell-derived Neurotrophic Factor; rRtGDNF)；重组大鼠胶质细胞源性神经营养因子

Synonyms

Astrocyte-derived trophic factor; ATF; ATF1; ATF2; glial cell derived neurotrophic factor; glial cell line derived neurotrophic factor; glial cell line-derived neurotrophic factor; HFB1-GDNF; hGDNF; HSCR3

Purity

>98% by SDS-PAGE and HPLC analyses.

Biological Activity

Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using rat C6 cells is less than 0.2ng/ml, corresponding to a specific activity of >5.0×10⁶IU/mg.

Physical Appearance

Sterile Filtered White lyophilized (freeze-dried) powder.

Formulation

Lyophilized from a 0.2μm filtered concentrated solution in 1X PBS, pH7.4.

Endotoxin

Less than 0.1EU/μg of rRtGDNF as determined by LAL method.

Reconstitution

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0mg/ml. Stock solutions should be apportioned into working aliquots and stored at ≤-20℃. Further dilutions should be made in appropriate buffered solutions.

Category

Cytokine

Background

Glial cell-derived neurotrophic factor is a founding member of the GDNF family of ligands (GFL) and has been shown to interact with GFRA2 and GDNF family receptor alpha 1. It is a small protein that potently promotes the survival and morphological differentiation of various neuronal. It may also modulate local neuronal effects in distal regions of the motor neuron. GDNF Recombinant rat GDNF (monomer) contains 134 amino acids residues, which is a disulfide-linked homodimer and it shares 99% and 93%a.a. sequence identity with mouse and human GDNF.

Amino Acid Sequence

SPDKQAAALP RRERNRQAAA ASPENSRGKG RRGQRGKNRG CVLTAIHLNV TDLGLGYETK EELIFRYCSG SCEAAETMYD KILKNLSRSR RLTSDKVGQA CCRPVAFDDD LSFLDDSLVY HILRKHSAKR CGCI

产品编号

产品名称

包装

P6411-2μg

Recombinant Rat GDNF

2μg

P6411-10μg

Recombinant Rat GDNF

10μg

P6411-100μg

Recombinant Rat GDNF

100μg

P6411-1mg

Recombinant Rat GDNF

1mg

-

说明书

1份