Recombinant Rat IL-2, Liquid

Species

Gene ID

Accession

Source

Length

MW

Tag

Rat

116562

P17108

E. coli

135aa

15.5kDa

－

About this Antibody

Name

Recombinant Rat IL-2, Liquid (Recombinant Rat Interleukin-2, Liquid; rRtIL-2, Liquid)；重组大鼠白细胞介素2，液体

Synonyms

aldesleukin; Aldesleukin; IL-2lymphokine; interleukin 2; interleukin-2; involved in regulation of T-cell clonal expansion; T cell growth factor; T-cell growth factor; TCGF

Purity

>97% by SDS-PAGE and HPLC analyses.

Biological Activity

Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using murine CTLL-2 cells is less than 0.2ng/ml, corresponding to a specific activity of >5.0×10⁶IU/mg.

Physical Appearance

Sterile Colorless liquid.

Formulation

A 0.2μm filtered concentrated sterile solution in 10mM sodium citrate, pH4.0, 30% glycerol.

Endotoxin

Less than 1EU/μg of rRtIL-2, Liquid as determined by LAL method.

Reconstitution

N/A

Category

Cytokine

Background

IL-2 is a powerful immunoregulatory lymphokine produced by T-cells in response to antigenic or mitogenic stimulation. It is expressed by CD4⁺ and CD8⁺ T cells, γδ T cells, B cells, dendritic cells, and eosinophils. IL-2/IL-2R signaling is required for Tcell proliferation and other fundamental functions which are essential for the immune response. The receptor for IL-2 consists of three subunits (55kDa IL2Rα, 75kDa IL2Rβ, 64kDa common gamma chain γc/IL2Rγ) that are present on the cell surface in varying preformed complexes. Recombinant rat IL-2 is a 15.3kDa protein containing 134 amino acid residues and it shares about 82%, 66%, 66%, 60% and 54% amino acid sequence identity with mouse, human, rhesus macaque, pig and equus caballus IL-2, respectively.

Amino Acid Sequence

APTSSPAKET QQHLEQLLLD LQVLLRGIDN YKNLKLPMML TFKFYLPKQA TELKHLQCLE NELGALQRVL DLTQSKSFHL EDAGNFISNI RVTVVKLKGS ENKFECQFDD EPATVVEFLR RWIAICQSII STMTQ

产品编号

产品名称

包装

P6258-5μg

Recombinant Rat IL-2, Liquid

5μg

P6258-20μg

Recombinant Rat IL-2, Liquid

20μg

P6258-100μg

Recombinant Rat IL-2, Liquid

100μg

P6258-1mg

Recombinant Rat IL-2, Liquid

1mg

-

说明书

1份