Recombinant Rat IL-7

Species

Gene ID

Accession

Source

Length

MW

Tag

Rat

25647

Q91Y32

E. coli

129aa

14.9kDa

－

About this Antibody

Name

Recombinant Rat IL-7 (Recombinant Rat Interleukin-7; rRtIL-7)；重组大鼠白细胞介素7

Synonyms

Lymphopoietin-1; PBGF; IL-7interleukin-7; interleukin 7

Purity

>95% by SDS-PAGE and HPLC analyses.

Biological Activity

Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using murine 2E8 cells is less than 2.0ng/ml, corresponding to a specific activity of >5.0×10⁵IU/mg.

Physical Appearance

Sterile Filtered White lyophilized (freeze-dried) powder.

Formulation

Lyophilized from a 0.2μm filtered concentrated solution in PBS, pH7.4.

Endotoxin

Less than 1EU/μg of rRtIL-7 as determined by LAL method.

Reconstitution

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0mg/ml. Stock solutions should be apportioned into working aliquots and stored at ≤-20℃. Further dilutions should be made in appropriate buffered solutions.

Category

Cytokine

Background

Interleukin-7 (IL-7) is encoded by the IL7 gene and secreted by stromal cells in the red marrow and thymus. It binds to the IL-7 receptor, a heterodimer consisting of IL-7 receptor alpha and IL-2 receptor gamma chain. IL-7 stimulates the differentiation of hematopoietic stem cells into lymphoid progenitor cells and also stimulates proliferation of B cells, T cells and NK cells. Furthermore, IL-7 as an immunotherapy agent has been examined in many human clinical trials for various malignancies and during HIV infection. Rat IL-7 contains 129 amino acid residues and has three disulfide bonds. In addition, it has approximately 57% and 88% amino acid sequence identity with human and murine IL-7.

Amino Acid Sequence

DCHIKDKDGK AFGSVLMISI NQLDKMTGTD SDCPNNEPNF FKKHLCDDTK EAAFLNRAAR KLRQFLKMNI SEEFNDHLLR VSDGTQTLVN CTSKEEKTIK EQKKNDPCFL KRLLREIKTC WNKILKGSI

产品编号

产品名称

包装

P6281-2μg

Recombinant Rat IL-7

2μg

P6281-10μg

Recombinant Rat IL-7

10μg

P6281-100μg

Recombinant Rat IL-7

100μg

P6281-1mg

Recombinant Rat IL-7

1mg

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说明书

1份