Recombinant Rat IP-10/CXCL10

Species

Gene ID

Accession

Source

Length

MW

Tag

Rat

245920

P48973

E. coli

77aa

8.7kDa

－

About this Antibody

Name

Recombinant Rat IP-10/CXCL10 (Recombinant Rat γ-Interferon Inducible Protein 10/CXCL10; rRtIP-10/CXCL10)；重组大鼠干扰素伽玛诱导的10千道尔顿蛋白/CXCL10

Synonyms

CRG-2; IP-10; C7; chemokine (C-X-C motif) ligand 10; crg-2; gIP-10; IFI10; INP10; IP-10; mob-1; SCYB10

Purity

>95% by SDS-PAGE and HPLC analyses.

Biological Activity

Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human CXCR3 transfected HEK293 cells is in a concentration range of 10-50ng/ml.

Physical Appearance

Sterile Filtered White lyophilized (freeze-dried) powder.

Formulation

Lyophilized from a 0.2μm filtered concentrated solution in PBS, pH7.4.

Endotoxin

Less than 1EU/μg of rRtIP-10/CXCL10 as determined by LAL method.

Reconstitution

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0mg/ml. Stock solutions should be apportioned into working aliquots and stored at ≤-20℃. Further dilutions should be made in appropriate buffered solutions.

Category

Chemokines

Background

CXCL10 also known as IP-10 is belonging to the CXC chemokine family. It is encoded by the CXCL10 gene, and in rat it is also named the Mob-1 gene. This gene was identified on the basis of differential expression in rat embryo fibroblasts. CXCL10 elicits its effects by binding to the cell surface chemokine receptor CXCR3. CXCL10 has been shown to be a chemoattractant for activated T-lymphocytes and monocytes/macrophages. It also has other roles, such as promotion of T cell adhesion to endothelial cells, and inhibition of bone marrow colony formation and angiogenesis. Rat CXCL10 shares approximately 68% amino acid sequence identity with human CXCL10.

Amino Acid Sequence

IPLARTVRCT CIDFHEQPLR PRAIGKLEII PASLSCPHVE IIATMKKNNE KRCLNPESEA IKSLLKAVSQ RRSKRAP

产品编号

产品名称

包装

P6879-5μg

Recombinant Rat IP-10/CXCL10

5μg

P6879-25μg

Recombinant Rat IP-10/CXCL10

25μg

P6879-100μg

Recombinant Rat IP-10/CXCL10

100μg

P6879-1mg

Recombinant Rat IP-10/CXCL10

1mg

-

说明书

1份