Recombinant Rat Lymphotactin/XCL1

Species

Gene ID

Accession

Source

Length

MW

Tag

Rat

171371

P51672

E. coli

93aa

10kDa

－

About this Antibody

Name

Recombinant Rat Lymphotactin/XCL1 (Recombinant Rat Lymphotactin/XCL1; rRtLymphotactin/XCL1)；重组大鼠淋巴细胞趋化因子/XCL1

Synonyms

Lymphotactin; C motif chemokine 1; Cytokine SCM-1; Small-inducible cytokine C1; Xcl1; Ltn; Scyc1

Purity

>97% by SDS-PAGE and HPLC analyses.

Biological Activity

Fully biologically active when compared to standard. The ED50 as determined by a chemotaxis bioassay using human XCR1 transfected murine BaF3 cells is less than 100ng/ml, corresponding to a specific activity of >1.0×10⁴IU/mg.

Physical Appearance

Sterile Filtered White lyophilized (freeze-dried) powder.

Formulation

Lyophilized from a 0.2μm filtered concentrated solution in PBS, pH 7.4.

Endotoxin

Less than 0.1EU/μg of rRtLymphotactin/XCL1 as determined by LAL method.

Reconstitution

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0mg/ml. Stock solutions should be apportioned into working aliquots and stored at ≤ -20℃. Further dilutions should be made in appropriate buffered solutions.

Category

Chemokines

Background

Chemokine (C motif) ligand (XCL1), as known as lymphotactin, is the only known member of the C-chemokine family and signals through the receptor XCR1, formally known as GPR5. The expression of lymphotactin is abundant in some activated T cells such as activated CD8⁺ T cells and other class I MHC restricted T cells. It is found in high levels in spleen, thymus, intestine and peripheral blood leukocytes, and at lower levels in lung, prostate gland and ovary. XCL1 induces its chemotactic function by binding to a chemokine receptor called XCR1. Recombinant Rat XCL1 which is a single non-glycosylated polypeptide chains containing 93 amino acids and it shares approximately 57% and 82% amino acid sequence homology with the human and murine XCL1.

Amino Acid Sequence

VGTEVLQESI CVSLRTQRLP VQKIKTYTIK EGAMRAVIFV TKRGLRICAD PQAKWVKTAI KTVDGRASAS KSKAETIPTQ AQRSASTAVT LTG

产品编号

产品名称

包装

P6899-5μg

Recombinant Rat Lymphotactin/XCL1

5μg

P6899-20μg

Recombinant Rat Lymphotactin/XCL1

20μg

P6899-100μg

Recombinant Rat Lymphotactin/XCL1

100μg

P6899-1mg

Recombinant Rat Lymphotactin/XCL1

1mg

-

说明书

1份