Recombinant Rat SDF-1β/CXCL12β

Species

Gene ID

Accession

Source

Length

MW

Tag

Rat

24772

Q80YV8

E. coli

72aa

8.4kDa

－

About this Antibody

Name

Recombinant Rat SDF-1β/CXCL12β (Recombinant Rat Stromal-Cell Derived Factor-1β/CXCL12β; rRtSDF-1β/CXCL12β)；重组大鼠基质细胞衍生因子1β/CXCL12β

Synonyms

SDF-1beta; SDF 1beta; SDF1B

Purity

>97% by SDS-PAGE and HPLC analyses.

Biological Activity

Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human peripheral blood monocytes is in a concentration range of 100-200ng/ml.

Physical Appearance

Sterile Filtered White lyophilized (freeze-dried) powder.

Formulation

Lyophilized from a 0.2μm filtered concentrated solution in 20mM PB, pH7.4, 150mM NaCl.

Endotoxin

Less than 1EU/μg of rRtSDF-1β/CXCL12β as determined by LAL method.

Reconstitution

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0mg/ml. Stock solutions should be apportioned into working aliquots and stored at ≤-20℃. Further dilutions should be made in appropriate buffered solutions.

Category

Chemokines

Background

CXCL12 also known as SDF-1 is belonging to the CXC chemokine family. Rat CXCL12 is expressed as two isoforms that differ only in the C-terminal tail. And both SDF-1 isoforms undergo proteolytic processing of the first two N-terminal amino acids. In all SDF-1 isoforms, SDF-1β is the canonical sequence. It has the complete amino acids in the C-terminal tail. On the cell surface, the receptor for this chemokine is CXCR4 and syndecan4. CXCL12 is strongly chemotactic for T-lymphocytes, monocytes, but not neutrophils. SDF-1 is highly conserved between species, murine CXCL12β shares approximately 96% amino acid sequence identity with human CXCL12β.

Amino Acid Sequence

KPVSLSYRCP CRFFESHVAR ANVKHLKILN TPNCALQIVA RLKSNNRQVC IDPKLKWIQE YLDKALNKRL KM

产品编号

产品名称

包装

P6888-2μg

Recombinant Rat SDF-1β/CXCL12β

2μg

P6888-10μg

Recombinant Rat SDF-1β/CXCL12β

10μg

P6888-100μg

Recombinant Rat SDF-1β/CXCL12β

100μg

P6888-1mg

Recombinant Rat SDF-1β/CXCL12β

1mg

-

说明书

1份