Recombinant Rhesus Macaque SAA1

Species

Gene ID

Accession

Source

Length

MW

Tag

Rhesus Macaque

694827

F6V9N7

E. coli

104aa

11.7kDa

－

About this Antibody

Name

Recombinant Rhesus Macaque SAA1 (Recombinant Rhesus Macaque Serum Amyloid A Protein-1; rRhSAA1)；重组恒河猴血清淀粉样蛋白A

Synonyms

PIG4; SAA1; MGC111216; PIG4; SAA; SAA2; serum amyloid A protein; serum amyloid A1; TP53I4; tumor protein p53 inducible protein 4

Purity

>97% by SDS-PAGE and HPLC analyses.

Biological Activity

Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human monocytes is in a concentration range of 10-100ng/ml.

Physical Appearance

Sterile Filtered White lyophilized (freeze-dried) powder.

Formulation

Lyophilized from a 0.2μm filtered concentrated solution in PBS, pH7.4.

Endotoxin

Less than 1EU/μg of rRhSAA1 as determined by LAL method.

Reconstitution

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0mg/ml. Stock solutions should be apportioned into working aliquots and stored at ≤-20℃. Further dilutions should be made in appropriate buffered solutions.

Category

Chemokines

Background

Serum Amyloid A protein-1 belongs to the SAA family of apolipoproteins that circulates in association with high-density lipoproteins (HDL). It is a multifunctional protein produced by hepatocytes in response to pro-inflammatory cytokines. SAA1 is a ligand for CD36/SR-B3, SR-B1, FPRL1, TLR2, and RAGE on monocytes/macrophages, inducing chemotaxis and generation of cytokines and tissue factor. It also can bind the surface of invading gram-negative bacteria, acting as an opsonin to aid clearance by macrophages. Additionally, SAA1 binds platelets, probably by engaging fibrinogen on the platelet surface.

Amino Acid Sequence

RSWFSFLGEA YDGARDMWRA YSDMKEANYK NSDKYFHARG NYDAAQRGPG GVWAAEVISD ARENIQKLLG RGAEDTLADQ AANEWGRSGK DPNHFRPAGL PEKY

产品编号

产品名称

包装

P6704-2μg

Recombinant Rhesus Macaque SAA1

2μg

P6704-10μg

Recombinant Rhesus Macaque SAA1

10μg

P6704-100μg

Recombinant Rhesus Macaque SAA1

100μg

P6704-1mg

Recombinant Rhesus Macaque SAA1

1mg

-

说明书

1份