Ubiquitin Rabbit Polyclonal Antibody

来源

用途

交叉反应性

分子量

Rabbit

WB, ICC, IHC, IF

H, M, R

10KDa

WB

IP

IF

IHC

ICC

FC

ELISA

ChIP

1:500-1:1000

-

1:200

1:200

1:200

-

-

-

About this Antibody

Name

Ubiquitin Rabbit Polyclonal Antibody

Category

Polyclonal antibody(pAb); Primary antibody

Isotype

IgG

Purification

Peptide affinity purified

About the Immunogen

Immunogen

This antibody is produced by immunizing rabbits with a synthetic peptide (KLH-coupled) corresponding to Ubiquitin.

Gene ID

7314

SwissProt

P62988

Synonyms

40S ribosomal protein S27a; CEP80; Ribosomal protein S27a; RPS27A; UBA52; UBA80; UBB; UBC; UBCEP1; UBCEP80; UBIQ; ubiquitin and ribosomal protein S27a; ubiquitin carboxyl extension protein 80; ubiquitin-CEP80

Category

Ubiquitin and Ubiquitin-like proteins

Background

Ubiquitin is a conserved polypeptide unit that plays an important role in the ubiquitin-proteasome pathway. Ubiquitin exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair; Lys-11-linked is involved in ERAD (endoplasmic reticulum-associated degradation) and in cell-cycle regulation; Lys-29-linked is involved in lysosomal degradation; Lys-33-linked is involved in kinase modification; Lys-48-linked is involved in protein degradation via the proteasome; Lys-63-linked is involved in endocytosis, DNA-damage responses as well as in signaling processes leading to activation of the transcription factor NF-kappa-B.

产品编号

产品名称

包装

AF0306

Ubiquitin Rabbit Polyclonal Antibody

50μl

AZ050

Western一抗稀释液

50ml

—

说明书

1份